merge: Labs overhaul — biomarker catalog, structured entry, dashboard-style chart, edit/undo, backfill

# Conflicts: # src/app/api/labs/route.ts
2026-11-08 12:32:43 +00:00 · 2026-06-16 21:17:09 +02:00
commit cc32e2adf7
@@ -5690,6 +5690,12 @@ paths:
        date-range filters. Each row carries a server-computed neutral `rangeStatus` and a `hasNote` flag (the encrypted
        note itself is not echoed).
      parameters:
+        - in: query
+          name: biomarkerId
+          schema:
+            type: string
+            minLength: 1
+            maxLength: 64
        - in: query
          name: analyte
          schema:
@@ -5759,6 +5765,10 @@ paths:
            schema:
              type: object
              properties:
+                biomarkerId:
+                  type: string
+                  minLength: 1
+                  maxLength: 64
                panel:
                  anyOf:
                    - type: string
@@ -5791,9 +5801,7 @@ paths:
                    - type: string
                      const: ""
              required:
-                - analyte
                - value
-                - unit
                - takenAt
      responses:
        "201":
@@ -5924,6 +5932,212 @@ paths:
        "404": *a8
        "422": *a3
        "429": *a4
+  /api/labs/restore:
+    post:
+      tags:
+        - Labs
+      summary: Restore soft-deleted lab results
+      description: Un-tombstones 1..200 of the caller's soft-deleted lab results in one pass (the delete-Undo affordance). A
+        foreign / live id is a silent no-op. Audits via the wide-event ledger.
+      requestBody:
+        required: true
+        content:
+          application/json:
+            schema:
+              $ref: "#/components/schemas/RestoreLabResultsRequest"
+      responses:
+        "200":
+          description: Restore count.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/RestoreLabResultsResponse"
+        "401": *a1
+        "422": *a3
+        "429": *a4
+  /api/biomarkers:
+    get:
+      tags:
+        - Labs
+      summary: List the caller's biomarker catalog
+      description: Returns every biomarker the caller has defined, name-ordered. Each carries its unit, reference bounds, and
+        decrypted context.
+      responses:
+        "200":
+          description: Biomarker catalog.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/ListBiomarkersEnvelope"
+        "401": *a1
+        "422": *a3
+        "429": *a4
+    post:
+      tags:
+        - Labs
+      summary: Define a biomarker
+      description: Creates a user-scoped biomarker. The optional context note is AES-256-GCM encrypted before write. Audits as
+        `biomarker.create`.
+      requestBody:
+        required: true
+        content:
+          application/json:
+            schema:
+              type: object
+              properties:
+                name:
+                  type: string
+                  minLength: 1
+                  maxLength: 120
+                unit:
+                  type: string
+                  minLength: 1
+                  maxLength: 40
+                lowerBound:
+                  type: number
+                upperBound:
+                  type: number
+                context:
+                  type: string
+                  maxLength: 2000
+                panel:
+                  anyOf:
+                    - type: string
+                      minLength: 1
+                      maxLength: 120
+                    - type: string
+                      const: ""
+              required:
+                - name
+                - unit
+      responses:
+        "201":
+          description: Created biomarker.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/CreateBiomarkerResponse"
+        "401": *a1
+        "409": &a10
+          description: A biomarker with this name already exists for the caller.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/ErrorEnvelope"
+        "422": *a3
+        "429": *a4
+  /api/biomarkers/{id}:
+    get:
+      tags:
+        - Labs
+      summary: Fetch a single biomarker
+      description: Returns the biomarker including its decrypted `context`. Cross-user rows surface as 404.
+      parameters:
+        - in: path
+          name: id
+          schema:
+            type: string
+          required: true
+      responses:
+        "200":
+          description: Biomarker detail.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/GetBiomarkerResponse"
+        "401": *a1
+        "404": &a9
+          description: Biomarker not found (or owned by another user).
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/ErrorEnvelope"
+        "422": *a3
+        "429": *a4
+    put:
+      tags:
+        - Labs
+      summary: Edit a biomarker
+      description: Partial edit; omitted fields are untouched, an explicit null clears `context` / `panel` / a bound. Audits
+        as `biomarker.update`.
+      parameters:
+        - in: path
+          name: id
+          schema:
+            type: string
+          required: true
+      requestBody:
+        required: true
+        content:
+          application/json:
+            schema:
+              type: object
+              properties:
+                name:
+                  type: string
+                  minLength: 1
+                  maxLength: 120
+                unit:
+                  type: string
+                  minLength: 1
+                  maxLength: 40
+                lowerBound:
+                  anyOf:
+                    - type: number
+                    - type: "null"
+                upperBound:
+                  anyOf:
+                    - type: number
+                    - type: "null"
+                context:
+                  anyOf:
+                    - type: string
+                      maxLength: 2000
+                    - type: "null"
+                panel:
+                  anyOf:
+                    - anyOf:
+                        - type: string
+                          minLength: 1
+                          maxLength: 120
+                        - type: string
+                          const: ""
+                    - type: "null"
+      responses:
+        "200":
+          description: Updated biomarker.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/UpdateBiomarkerResponse"
+        "401": *a1
+        "404": *a9
+        "409": *a10
+        "422": *a3
+        "429": *a4
+    delete:
+      tags:
+        - Labs
+      summary: Delete a biomarker
+      description: "Hard-deletes the catalog definition. The `onDelete: SetNull` FK unlinks every reading (they keep their
+        legacy `analyte` / `unit`), so the history survives. Audits as `biomarker.delete`."
+      parameters:
+        - in: path
+          name: id
+          schema:
+            type: string
+          required: true
+      responses:
+        "200":
+          description: Deletion succeeded.
+          content:
+            application/json:
+              schema:
+                $ref: "#/components/schemas/DeleteBiomarkerResponse"
+        "401": *a1
+        "404": *a9
+        "422": *a3
+        "429": *a4
 components:
  schemas:
    PasskeyLoginVerifyRequest:
@@ -7239,6 +7453,17 @@ components:
          type: boolean
      description: Partial edit of a Vorsorge reminder. Omitted fields are left untouched; nextDueAt is recomputed server-side
        after the patch applies.
+    RestoreLabResultsRequest:
+      type: object
+      properties:
+        ids:
+          minItems: 1
+          maxItems: 200
+          type: array
+          items:
+            type: string
+      required:
+        - ids
    MedicationTreatmentClass:
      type: string
      enum:
@@ -17126,6 +17351,10 @@ components:
      properties:
        id:
          type: string
+        biomarkerId:
+          anyOf:
+            - type: string
+            - type: "null"
        panel:
          anyOf:
            - type: string
@@ -17158,6 +17387,7 @@ components:
          type: string
      required:
        - id
+        - biomarkerId
        - panel
        - analyte
        - value
@@ -17171,8 +17401,10 @@ components:
        - createdAt
        - updatedAt
      additionalProperties: false
-      description: A stored lab result. The encrypted note is never echoed in list rows; `hasNote` flags its presence and the
-        single-resource GET returns the decrypted `note`.
+      description: A stored lab result. `biomarkerId` links the user-scoped catalog marker (null for legacy free-text rows);
+        when linked, `analyte` / `unit` / `referenceLow` / `referenceHigh` are RESOLVED server-side from the Biomarker —
+        the client renders them and never recomputes the range. The encrypted note is never echoed in list rows;
+        `hasNote` flags its presence and the single-resource GET returns the decrypted `note`.
    LabReferenceRangeStatus:
      type: string
      enum:
@@ -17222,6 +17454,10 @@ components:
      properties:
        id:
          type: string
+        biomarkerId:
+          anyOf:
+            - type: string
+            - type: "null"
        panel:
          anyOf:
            - type: string
@@ -17256,6 +17492,7 @@ components:
            - type: "null"
      required:
        - id
+        - biomarkerId
        - panel
        - analyte
        - value
@@ -17310,6 +17547,175 @@ components:
        - data
        - error
      additionalProperties: false
+    RestoreLabResultsResponse:
+      type: object
+      properties:
+        data:
+          type: object
+          properties:
+            restored:
+              type: number
+          required:
+            - restored
+          additionalProperties: false
+        error:
+          type: "null"
+        meta:
+          type: object
+          properties:
+            requestId:
+              type: string
+          additionalProperties: false
+      required:
+        - data
+        - error
+      additionalProperties: false
+    ListBiomarkersEnvelope:
+      type: object
+      properties:
+        data:
+          $ref: "#/components/schemas/ListBiomarkersResponse"
+        error:
+          type: "null"
+        meta:
+          type: object
+          properties:
+            requestId:
+              type: string
+          additionalProperties: false
+      required:
+        - data
+        - error
+      additionalProperties: false
+    ListBiomarkersResponse:
+      type: object
+      properties:
+        biomarkers:
+          type: array
+          items:
+            $ref: "#/components/schemas/Biomarker"
+      required:
+        - biomarkers
+      additionalProperties: false
+    Biomarker:
+      type: object
+      properties:
+        id:
+          type: string
+        name:
+          type: string
+        unit:
+          type: string
+        lowerBound:
+          anyOf:
+            - type: number
+            - type: "null"
+        upperBound:
+          anyOf:
+            - type: number
+            - type: "null"
+        panel:
+          anyOf:
+            - type: string
+            - type: "null"
+        hasContext:
+          type: boolean
+        context:
+          anyOf:
+            - type: string
+            - type: "null"
+        createdAt:
+          type: string
+        updatedAt:
+          type: string
+      required:
+        - id
+        - name
+        - unit
+        - lowerBound
+        - upperBound
+        - panel
+        - hasContext
+        - context
+        - createdAt
+        - updatedAt
+      additionalProperties: false
+      description: A user-scoped catalog marker. `context` is the decrypted per-marker note (or null); `hasContext` flags its
+        presence. A `LabResult` linking this marker resolves its unit + reference bounds from here.
+    CreateBiomarkerResponse:
+      type: object
+      properties:
+        data:
+          $ref: "#/components/schemas/Biomarker"
+        error:
+          type: "null"
+        meta:
+          type: object
+          properties:
+            requestId:
+              type: string
+          additionalProperties: false
+      required:
+        - data
+        - error
+      additionalProperties: false
+    GetBiomarkerResponse:
+      type: object
+      properties:
+        data:
+          $ref: "#/components/schemas/Biomarker"
+        error:
+          type: "null"
+        meta:
+          type: object
+          properties:
+            requestId:
+              type: string
+          additionalProperties: false
+      required:
+        - data
+        - error
+      additionalProperties: false
+    UpdateBiomarkerResponse:
+      type: object
+      properties:
+        data:
+          $ref: "#/components/schemas/Biomarker"
+        error:
+          type: "null"
+        meta:
+          type: object
+          properties:
+            requestId:
+              type: string
+          additionalProperties: false
+      required:
+        - data
+        - error
+      additionalProperties: false
+    DeleteBiomarkerResponse:
+      type: object
+      properties:
+        data:
+          type: object
+          properties:
+            deleted:
+              type: boolean
+          required:
+            - deleted
+          additionalProperties: false
+        error:
+          type: "null"
+        meta:
+          type: object
+          properties:
+            requestId:
+              type: string
+          additionalProperties: false
+      required:
+        - data
+        - error
+      additionalProperties: false
    MedicationScheduleOutput:
      type: object
      properties:
@@ -6516,13 +6516,13 @@
  "labs": {
    "title": "Laborwerte",
    "subtitle": "Blutwerte und Biomarker",
-    "addResult": "Hinzufügen",
+    "addResult": "Wert hinzufügen",
    "addDescription": "Erfasse einen Biomarker aus deinem Laborbefund.",
    "addFirst": "Ersten Wert erfassen",
    "emptyTitle": "Noch keine Laborwerte",
    "emptyDescription": "Erfasse Blutwerte wie HbA1c, LDL oder Ferritin, um sie über die Zeit zu verfolgen und mit deiner Ärztin oder deinem Arzt zu teilen.",
    "referenceLabel": "Referenz",
-    "readingsCount": "{count} Werte",
+    "readingsCount": "{count} Messungen",
    "deleteLatest": "Letzten Wert löschen",
    "deleteConfirmTitle": "Laborwert löschen?",
    "deleteConfirmDescription": "Dieser Laborwert wird dauerhaft gelöscht.",
@@ -6551,11 +6551,127 @@
      "referenceHint": "Übernimm den Referenzbereich aus deinem Laborbefund. Beide Grenzen sind optional.",
      "note": "Notiz",
      "notePlaceholder": "Optionaler Kontext zu diesem Wert",
-      "requiredError": "Biomarker, Wert und Einheit sind erforderlich.",
+      "requiredError": "Bitte einen Wert eingeben.",
      "rangeOrderError": "Die untere Referenz darf nicht über der oberen liegen.",
      "save": "Speichern",
      "savedToast": "Wert gespeichert",
-      "saveError": "Wert konnte nicht gespeichert werden"
+      "saveError": "Wert konnte nicht gespeichert werden",
+      "biomarker": "Biomarker",
+      "biomarkerPlaceholder": "Biomarker auswählen",
+      "defineNew": "+ Neuen Biomarker anlegen",
+      "noBiomarkersHint": "Lege zuerst einen Biomarker an, um einen Wert zu erfassen.",
+      "pickBiomarkerError": "Bitte zuerst einen Biomarker auswählen."
+    },
+    "backToLabs": "Zurück zu den Laborwerten",
+    "hasNote": "Notiz",
+    "editTitle": "Wert bearbeiten",
+    "editDescription": "Wert, Datum oder Notiz dieser Messung korrigieren.",
+    "editedToast": "Wert aktualisiert",
+    "editError": "Wert konnte nicht aktualisiert werden",
+    "editTimestampError": "Bitte ein gültiges Datum eingeben.",
+    "editReading": "Wert bearbeiten",
+    "deleteReading": "Wert löschen",
+    "restoredToast": "Wert wiederhergestellt",
+    "restoreError": "Wert konnte nicht wiederhergestellt werden",
+    "detail": {
+      "history": "Verlauf",
+      "emptyTitle": "Noch keine Werte",
+      "emptyDescription": "Füge einen Wert hinzu, um diesen Biomarker über die Zeit zu verfolgen."
+    },
+    "chart": {
+      "empty": "Keine Werte in diesem Zeitraum.",
+      "valueLabel": "Wert",
+      "range": {
+        "30": "30 T",
+        "90": "90 T",
+        "365": "1 J",
+        "all": "Alle"
+      }
+    },
+    "biomarker": {
+      "manage": "Biomarker",
+      "manageTitle": "Biomarker",
+      "manageSheetDescription": "Lege die Marker an, die du verfolgst. Jeder wird einmal mit Einheit und Referenzbereich eingerichtet.",
+      "managerDescription": "Marker einmal definieren — Einheit und Bereich gelten für jede Messung.",
+      "define": "Anlegen",
+      "defineFirst": "Ersten Biomarker anlegen",
+      "defineTitle": "Biomarker anlegen",
+      "defineDescription": "Name, Einheit und Referenzbereich einmalig festlegen. Beim Erfassen wählst du nur den Marker.",
+      "editTitle": "Biomarker bearbeiten",
+      "edit": "Bearbeiten",
+      "delete": "Löschen",
+      "deletedToast": "Biomarker gelöscht",
+      "deleteError": "Biomarker konnte nicht gelöscht werden",
+      "deleteConfirmTitle": "Biomarker löschen?",
+      "deleteConfirmDescription": "Die Definition wird entfernt. Bestehende Werte bleiben erhalten, aber ohne Verknüpfung.",
+      "emptyTitle": "Noch keine Biomarker",
+      "emptyDescription": "Lege Marker wie LDL oder HbA1c an, um Werte zu erfassen.",
+      "loadError": "Biomarker konnten nicht geladen werden",
+      "noRange": "Kein Referenzbereich",
+      "form": {
+        "seedLabel": "Von einem gängigen Marker starten",
+        "seedPlaceholder": "Marker wählen (optional)",
+        "seedHint": "Eine Auswahl füllt die Felder unten — passe den Bereich an dein Labor an.",
+        "name": "Name",
+        "namePlaceholder": "z. B. LDL-Cholesterin",
+        "unit": "Einheit",
+        "unitPlaceholder": "z. B. mg/dl",
+        "panel": "Panel",
+        "panelPlaceholder": "z. B. Lipide",
+        "lowerBound": "Referenz unten",
+        "upperBound": "Referenz oben",
+        "lowerPlaceholder": "Untere Grenze",
+        "upperPlaceholder": "Obere Grenze",
+        "context": "Kontext",
+        "contextPlaceholder": "Optionale Notiz zu diesem Marker",
+        "rangeHint": "Beide Grenzen sind optional — eine leer lassen für einen offenen Bereich (z. B. LDL < 116).",
+        "requiredError": "Name und Einheit sind erforderlich.",
+        "rangeOrderError": "Die untere Grenze darf die obere nicht überschreiten.",
+        "save": "Biomarker speichern",
+        "savedToast": "Biomarker gespeichert",
+        "updatedToast": "Biomarker aktualisiert",
+        "saveError": "Biomarker konnte nicht gespeichert werden"
+      }
+    },
+    "catalog": {
+      "total-cholesterol": "Gesamtcholesterin",
+      "ldl": "LDL-Cholesterin",
+      "hdl": "HDL-Cholesterin",
+      "triglycerides": "Triglyceride",
+      "fasting-glucose": "Nüchternglukose",
+      "hba1c": "HbA1c",
+      "tsh": "TSH",
+      "ft3": "Freies T3",
+      "ft4": "Freies T4",
+      "ferritin": "Ferritin",
+      "transferrin-saturation": "Transferrinsättigung",
+      "vitamin-d": "Vitamin D (25-OH)",
+      "vitamin-b12": "Vitamin B12",
+      "folate": "Folsäure",
+      "hs-crp": "hs-CRP",
+      "creatinine": "Kreatinin",
+      "egfr": "eGFR",
+      "alt": "ALT (GPT)",
+      "ast": "AST (GOT)",
+      "ggt": "GGT",
+      "sodium": "Natrium",
+      "potassium": "Kalium",
+      "hemoglobin": "Hämoglobin",
+      "hematocrit": "Hämatokrit",
+      "wbc": "Leukozyten",
+      "platelets": "Thrombozyten",
+      "panel": {
+        "lipids": "Lipide",
+        "glucose": "Glukosestoffwechsel",
+        "thyroid": "Schilddrüse",
+        "iron": "Eisen",
+        "vitamins": "Vitamine",
+        "inflammation": "Entzündung",
+        "renal": "Niere",
+        "liver": "Leber",
+        "electrolytes": "Elektrolyte",
+        "bloodCount": "Blutbild"
+      }
    }
  },
  "modules": {
@@ -6516,7 +6516,7 @@
  "labs": {
    "title": "Lab results",
    "subtitle": "Bloodwork and biomarker readings",
-    "addResult": "Add",
+    "addResult": "Add value",
    "addDescription": "Record a biomarker reading from a lab report.",
    "addFirst": "Add your first result",
    "emptyTitle": "No lab results yet",
@@ -6551,11 +6551,127 @@
      "referenceHint": "Copy the reference range from your lab report. Either bound is optional.",
      "note": "Note",
      "notePlaceholder": "Optional context for this result",
-      "requiredError": "Biomarker, value and unit are required.",
+      "requiredError": "Enter a value.",
      "rangeOrderError": "The reference low must not exceed the reference high.",
      "save": "Save",
      "savedToast": "Result saved",
-      "saveError": "Could not save the result"
+      "saveError": "Could not save the result",
+      "biomarker": "Biomarker",
+      "biomarkerPlaceholder": "Pick a biomarker",
+      "defineNew": "+ Define new biomarker",
+      "noBiomarkersHint": "Define a biomarker first to record a value against it.",
+      "pickBiomarkerError": "Pick a biomarker first."
+    },
+    "backToLabs": "Back to lab results",
+    "hasNote": "Note",
+    "editTitle": "Edit reading",
+    "editDescription": "Correct the value, date or note of this reading.",
+    "editedToast": "Reading updated",
+    "editError": "Could not update the reading",
+    "editTimestampError": "Enter a valid date.",
+    "editReading": "Edit reading",
+    "deleteReading": "Delete reading",
+    "restoredToast": "Reading restored",
+    "restoreError": "Could not restore the reading",
+    "detail": {
+      "history": "History",
+      "emptyTitle": "No readings yet",
+      "emptyDescription": "Add a value to start tracking this biomarker over time."
+    },
+    "chart": {
+      "empty": "No readings in this period.",
+      "valueLabel": "Value",
+      "range": {
+        "30": "30d",
+        "90": "90d",
+        "365": "1y",
+        "all": "All"
+      }
+    },
+    "biomarker": {
+      "manage": "Biomarkers",
+      "manageTitle": "Biomarkers",
+      "manageSheetDescription": "Define the markers you track. Each is set up once with its unit and reference range.",
+      "managerDescription": "Define a marker once — its unit and range are reused for every reading.",
+      "define": "Define",
+      "defineFirst": "Define your first biomarker",
+      "defineTitle": "Define biomarker",
+      "defineDescription": "Set the name, unit and reference range once. You pick the marker when adding a value.",
+      "editTitle": "Edit biomarker",
+      "edit": "Edit",
+      "delete": "Delete",
+      "deletedToast": "Biomarker deleted",
+      "deleteError": "Could not delete the biomarker",
+      "deleteConfirmTitle": "Delete biomarker?",
+      "deleteConfirmDescription": "The definition is removed. Existing readings are kept but unlinked.",
+      "emptyTitle": "No biomarkers yet",
+      "emptyDescription": "Define markers like LDL or HbA1c to record values against them.",
+      "loadError": "Could not load biomarkers",
+      "noRange": "No reference range",
+      "form": {
+        "seedLabel": "Start from a common marker",
+        "seedPlaceholder": "Choose a marker (optional)",
+        "seedHint": "Picking one fills the fields below — adjust the range to match your lab.",
+        "name": "Name",
+        "namePlaceholder": "e.g. LDL cholesterol",
+        "unit": "Unit",
+        "unitPlaceholder": "e.g. mg/dL",
+        "panel": "Panel",
+        "panelPlaceholder": "e.g. Lipids",
+        "lowerBound": "Reference low",
+        "upperBound": "Reference high",
+        "lowerPlaceholder": "Lower bound",
+        "upperPlaceholder": "Upper bound",
+        "context": "Context",
+        "contextPlaceholder": "Optional note about this marker",
+        "rangeHint": "Either bound is optional — leave one blank for an open-ended range (e.g. LDL < 116).",
+        "requiredError": "Name and unit are required.",
+        "rangeOrderError": "The lower bound must not exceed the upper bound.",
+        "save": "Save biomarker",
+        "savedToast": "Biomarker saved",
+        "updatedToast": "Biomarker updated",
+        "saveError": "Could not save the biomarker"
+      }
+    },
+    "catalog": {
+      "total-cholesterol": "Total cholesterol",
+      "ldl": "LDL cholesterol",
+      "hdl": "HDL cholesterol",
+      "triglycerides": "Triglycerides",
+      "fasting-glucose": "Fasting glucose",
+      "hba1c": "HbA1c",
+      "tsh": "TSH",
+      "ft3": "Free T3",
+      "ft4": "Free T4",
+      "ferritin": "Ferritin",
+      "transferrin-saturation": "Transferrin saturation",
+      "vitamin-d": "Vitamin D (25-OH)",
+      "vitamin-b12": "Vitamin B12",
+      "folate": "Folate",
+      "hs-crp": "hs-CRP",
+      "creatinine": "Creatinine",
+      "egfr": "eGFR",
+      "alt": "ALT",
+      "ast": "AST",
+      "ggt": "GGT",
+      "sodium": "Sodium",
+      "potassium": "Potassium",
+      "hemoglobin": "Hemoglobin",
+      "hematocrit": "Hematocrit",
+      "wbc": "White blood cells",
+      "platelets": "Platelets",
+      "panel": {
+        "lipids": "Lipids",
+        "glucose": "Glucose metabolism",
+        "thyroid": "Thyroid",
+        "iron": "Iron",
+        "vitamins": "Vitamins",
+        "inflammation": "Inflammation",
+        "renal": "Kidney",
+        "liver": "Liver",
+        "electrolytes": "Electrolytes",
+        "bloodCount": "Blood count"
+      }
    }
  },
  "modules": {
@@ -6516,13 +6516,13 @@
  "labs": {
    "title": "Resultados de análisis",
    "subtitle": "Analíticas de sangre y biomarcadores",
-    "addResult": "Añadir",
+    "addResult": "Añadir valor",
    "addDescription": "Registra un biomarcador a partir de un informe de laboratorio.",
    "addFirst": "Añade tu primer resultado",
    "emptyTitle": "Aún no hay resultados",
    "emptyDescription": "Registra analíticas como HbA1c, LDL o ferritina para seguirlas a lo largo del tiempo y compartirlas con tu médico.",
    "referenceLabel": "Referencia",
-    "readingsCount": "{count} valores",
+    "readingsCount": "{count} mediciones",
    "deleteLatest": "Eliminar el último valor",
    "deleteConfirmTitle": "¿Eliminar resultado de laboratorio?",
    "deleteConfirmDescription": "Este resultado de laboratorio se eliminará de forma permanente.",
@@ -6551,11 +6551,127 @@
      "referenceHint": "Copia el rango de referencia de tu informe de laboratorio. Cualquiera de los límites es opcional.",
      "note": "Nota",
      "notePlaceholder": "Contexto opcional para este resultado",
-      "requiredError": "El biomarcador, el valor y la unidad son obligatorios.",
+      "requiredError": "Introduce un valor.",
      "rangeOrderError": "La referencia mínima no puede superar la máxima.",
      "save": "Guardar",
      "savedToast": "Resultado guardado",
-      "saveError": "No se pudo guardar el resultado"
+      "saveError": "No se pudo guardar el resultado",
+      "biomarker": "Biomarcador",
+      "biomarkerPlaceholder": "Elige un biomarcador",
+      "defineNew": "+ Definir nuevo biomarcador",
+      "noBiomarkersHint": "Define primero un biomarcador para registrar un valor.",
+      "pickBiomarkerError": "Elige primero un biomarcador."
+    },
+    "backToLabs": "Volver a los resultados",
+    "hasNote": "Nota",
+    "editTitle": "Editar medición",
+    "editDescription": "Corrige el valor, la fecha o la nota de esta medición.",
+    "editedToast": "Medición actualizada",
+    "editError": "No se pudo actualizar la medición",
+    "editTimestampError": "Introduce una fecha válida.",
+    "editReading": "Editar medición",
+    "deleteReading": "Eliminar medición",
+    "restoredToast": "Medición restaurada",
+    "restoreError": "No se pudo restaurar la medición",
+    "detail": {
+      "history": "Historial",
+      "emptyTitle": "Aún no hay mediciones",
+      "emptyDescription": "Añade un valor para seguir este biomarcador con el tiempo."
+    },
+    "chart": {
+      "empty": "Sin mediciones en este periodo.",
+      "valueLabel": "Valor",
+      "range": {
+        "30": "30 d",
+        "90": "90 d",
+        "365": "1 a",
+        "all": "Todo"
+      }
+    },
+    "biomarker": {
+      "manage": "Biomarcadores",
+      "manageTitle": "Biomarcadores",
+      "manageSheetDescription": "Define los marcadores que sigues. Cada uno se configura una vez con su unidad y rango de referencia.",
+      "managerDescription": "Define un marcador una vez: su unidad y rango se reutilizan en cada medición.",
+      "define": "Definir",
+      "defineFirst": "Define tu primer biomarcador",
+      "defineTitle": "Definir biomarcador",
+      "defineDescription": "Configura el nombre, la unidad y el rango una vez. Eliges el marcador al añadir un valor.",
+      "editTitle": "Editar biomarcador",
+      "edit": "Editar",
+      "delete": "Eliminar",
+      "deletedToast": "Biomarcador eliminado",
+      "deleteError": "No se pudo eliminar el biomarcador",
+      "deleteConfirmTitle": "¿Eliminar biomarcador?",
+      "deleteConfirmDescription": "Se elimina la definición. Las mediciones existentes se conservan pero se desvinculan.",
+      "emptyTitle": "Aún no hay biomarcadores",
+      "emptyDescription": "Define marcadores como LDL o HbA1c para registrar valores.",
+      "loadError": "No se pudieron cargar los biomarcadores",
+      "noRange": "Sin rango de referencia",
+      "form": {
+        "seedLabel": "Partir de un marcador común",
+        "seedPlaceholder": "Elige un marcador (opcional)",
+        "seedHint": "Al elegir uno se rellenan los campos: ajusta el rango a tu laboratorio.",
+        "name": "Nombre",
+        "namePlaceholder": "p. ej. Colesterol LDL",
+        "unit": "Unidad",
+        "unitPlaceholder": "p. ej. mg/dL",
+        "panel": "Panel",
+        "panelPlaceholder": "p. ej. Lípidos",
+        "lowerBound": "Referencia mínima",
+        "upperBound": "Referencia máxima",
+        "lowerPlaceholder": "Límite inferior",
+        "upperPlaceholder": "Límite superior",
+        "context": "Contexto",
+        "contextPlaceholder": "Nota opcional sobre este marcador",
+        "rangeHint": "Ambos límites son opcionales: deja uno en blanco para un rango abierto (p. ej. LDL < 116).",
+        "requiredError": "El nombre y la unidad son obligatorios.",
+        "rangeOrderError": "El límite inferior no debe superar al superior.",
+        "save": "Guardar biomarcador",
+        "savedToast": "Biomarcador guardado",
+        "updatedToast": "Biomarcador actualizado",
+        "saveError": "No se pudo guardar el biomarcador"
+      }
+    },
+    "catalog": {
+      "total-cholesterol": "Colesterol total",
+      "ldl": "Colesterol LDL",
+      "hdl": "Colesterol HDL",
+      "triglycerides": "Triglicéridos",
+      "fasting-glucose": "Glucosa en ayunas",
+      "hba1c": "HbA1c",
+      "tsh": "TSH",
+      "ft3": "T3 libre",
+      "ft4": "T4 libre",
+      "ferritin": "Ferritina",
+      "transferrin-saturation": "Saturación de transferrina",
+      "vitamin-d": "Vitamina D (25-OH)",
+      "vitamin-b12": "Vitamina B12",
+      "folate": "Folato",
+      "hs-crp": "PCR ultrasensible",
+      "creatinine": "Creatinina",
+      "egfr": "TFGe",
+      "alt": "ALT",
+      "ast": "AST",
+      "ggt": "GGT",
+      "sodium": "Sodio",
+      "potassium": "Potasio",
+      "hemoglobin": "Hemoglobina",
+      "hematocrit": "Hematocrito",
+      "wbc": "Leucocitos",
+      "platelets": "Plaquetas",
+      "panel": {
+        "lipids": "Lípidos",
+        "glucose": "Metabolismo de la glucosa",
+        "thyroid": "Tiroides",
+        "iron": "Hierro",
+        "vitamins": "Vitaminas",
+        "inflammation": "Inflamación",
+        "renal": "Riñón",
+        "liver": "Hígado",
+        "electrolytes": "Electrolitos",
+        "bloodCount": "Hemograma"
+      }
    }
  },
  "modules": {
@@ -6516,13 +6516,13 @@
  "labs": {
    "title": "Résultats d'analyses",
    "subtitle": "Analyses sanguines et biomarqueurs",
-    "addResult": "Ajouter",
+    "addResult": "Ajouter une valeur",
    "addDescription": "Enregistrez un biomarqueur à partir d'un compte rendu de laboratoire.",
    "addFirst": "Ajouter votre premier résultat",
    "emptyTitle": "Aucun résultat pour l'instant",
    "emptyDescription": "Enregistrez des analyses comme l'HbA1c, le LDL ou la ferritine pour les suivre dans le temps et les partager avec votre médecin.",
    "referenceLabel": "Référence",
-    "readingsCount": "{count} valeurs",
+    "readingsCount": "{count} mesures",
    "deleteLatest": "Supprimer la dernière valeur",
    "deleteConfirmTitle": "Supprimer le résultat d'analyse ?",
    "deleteConfirmDescription": "Ce résultat d'analyse sera définitivement supprimé.",
@@ -6551,11 +6551,127 @@
      "referenceHint": "Reprenez l'intervalle de référence de votre compte rendu. Chaque borne est facultative.",
      "note": "Note",
      "notePlaceholder": "Contexte facultatif pour ce résultat",
-      "requiredError": "Le biomarqueur, la valeur et l'unité sont obligatoires.",
+      "requiredError": "Saisissez une valeur.",
      "rangeOrderError": "La référence basse ne doit pas dépasser la référence haute.",
      "save": "Enregistrer",
      "savedToast": "Résultat enregistré",
-      "saveError": "Impossible d'enregistrer le résultat"
+      "saveError": "Impossible d'enregistrer le résultat",
+      "biomarker": "Biomarqueur",
+      "biomarkerPlaceholder": "Choisir un biomarqueur",
+      "defineNew": "+ Définir un nouveau biomarqueur",
+      "noBiomarkersHint": "Définissez d'abord un biomarqueur pour enregistrer une valeur.",
+      "pickBiomarkerError": "Choisissez d'abord un biomarqueur."
+    },
+    "backToLabs": "Retour aux résultats",
+    "hasNote": "Note",
+    "editTitle": "Modifier la mesure",
+    "editDescription": "Corrigez la valeur, la date ou la note de cette mesure.",
+    "editedToast": "Mesure mise à jour",
+    "editError": "Impossible de mettre à jour la mesure",
+    "editTimestampError": "Saisissez une date valide.",
+    "editReading": "Modifier la mesure",
+    "deleteReading": "Supprimer la mesure",
+    "restoredToast": "Mesure restaurée",
+    "restoreError": "Impossible de restaurer la mesure",
+    "detail": {
+      "history": "Historique",
+      "emptyTitle": "Aucune mesure pour l'instant",
+      "emptyDescription": "Ajoutez une valeur pour suivre ce biomarqueur dans le temps."
+    },
+    "chart": {
+      "empty": "Aucune mesure sur cette période.",
+      "valueLabel": "Valeur",
+      "range": {
+        "30": "30 j",
+        "90": "90 j",
+        "365": "1 a",
+        "all": "Tout"
+      }
+    },
+    "biomarker": {
+      "manage": "Biomarqueurs",
+      "manageTitle": "Biomarqueurs",
+      "manageSheetDescription": "Définissez les marqueurs que vous suivez. Chacun est configuré une fois avec son unité et sa plage de référence.",
+      "managerDescription": "Définissez un marqueur une fois — son unité et sa plage sont réutilisées pour chaque mesure.",
+      "define": "Définir",
+      "defineFirst": "Définir votre premier biomarqueur",
+      "defineTitle": "Définir un biomarqueur",
+      "defineDescription": "Réglez le nom, l'unité et la plage une fois. Vous choisissez le marqueur à l'ajout d'une valeur.",
+      "editTitle": "Modifier le biomarqueur",
+      "edit": "Modifier",
+      "delete": "Supprimer",
+      "deletedToast": "Biomarqueur supprimé",
+      "deleteError": "Impossible de supprimer le biomarqueur",
+      "deleteConfirmTitle": "Supprimer le biomarqueur ?",
+      "deleteConfirmDescription": "La définition est supprimée. Les mesures existantes sont conservées mais dissociées.",
+      "emptyTitle": "Aucun biomarqueur pour l'instant",
+      "emptyDescription": "Définissez des marqueurs comme LDL ou HbA1c pour enregistrer des valeurs.",
+      "loadError": "Impossible de charger les biomarqueurs",
+      "noRange": "Pas de plage de référence",
+      "form": {
+        "seedLabel": "Partir d'un marqueur courant",
+        "seedPlaceholder": "Choisir un marqueur (facultatif)",
+        "seedHint": "En choisir un remplit les champs — ajustez la plage à votre laboratoire.",
+        "name": "Nom",
+        "namePlaceholder": "ex. Cholestérol LDL",
+        "unit": "Unité",
+        "unitPlaceholder": "ex. mg/dL",
+        "panel": "Panel",
+        "panelPlaceholder": "ex. Lipides",
+        "lowerBound": "Référence basse",
+        "upperBound": "Référence haute",
+        "lowerPlaceholder": "Borne inférieure",
+        "upperPlaceholder": "Borne supérieure",
+        "context": "Contexte",
+        "contextPlaceholder": "Note facultative sur ce marqueur",
+        "rangeHint": "Les deux bornes sont facultatives — laissez-en une vide pour une plage ouverte (ex. LDL < 116).",
+        "requiredError": "Le nom et l'unité sont requis.",
+        "rangeOrderError": "La borne inférieure ne doit pas dépasser la borne supérieure.",
+        "save": "Enregistrer le biomarqueur",
+        "savedToast": "Biomarqueur enregistré",
+        "updatedToast": "Biomarqueur mis à jour",
+        "saveError": "Impossible d'enregistrer le biomarqueur"
+      }
+    },
+    "catalog": {
+      "total-cholesterol": "Cholestérol total",
+      "ldl": "Cholestérol LDL",
+      "hdl": "Cholestérol HDL",
+      "triglycerides": "Triglycérides",
+      "fasting-glucose": "Glycémie à jeun",
+      "hba1c": "HbA1c",
+      "tsh": "TSH",
+      "ft3": "T3 libre",
+      "ft4": "T4 libre",
+      "ferritin": "Ferritine",
+      "transferrin-saturation": "Saturation de la transferrine",
+      "vitamin-d": "Vitamine D (25-OH)",
+      "vitamin-b12": "Vitamine B12",
+      "folate": "Folate",
+      "hs-crp": "CRP us",
+      "creatinine": "Créatinine",
+      "egfr": "DFGe",
+      "alt": "ALAT",
+      "ast": "ASAT",
+      "ggt": "GGT",
+      "sodium": "Sodium",
+      "potassium": "Potassium",
+      "hemoglobin": "Hémoglobine",
+      "hematocrit": "Hématocrite",
+      "wbc": "Leucocytes",
+      "platelets": "Plaquettes",
+      "panel": {
+        "lipids": "Lipides",
+        "glucose": "Métabolisme du glucose",
+        "thyroid": "Thyroïde",
+        "iron": "Fer",
+        "vitamins": "Vitamines",
+        "inflammation": "Inflammation",
+        "renal": "Rein",
+        "liver": "Foie",
+        "electrolytes": "Électrolytes",
+        "bloodCount": "Numération sanguine"
+      }
    }
  },
  "modules": {
@@ -6516,13 +6516,13 @@
  "labs": {
    "title": "Risultati degli esami",
    "subtitle": "Analisi del sangue e biomarcatori",
-    "addResult": "Aggiungi",
+    "addResult": "Aggiungi valore",
    "addDescription": "Registra un biomarcatore da un referto di laboratorio.",
    "addFirst": "Aggiungi il primo risultato",
    "emptyTitle": "Ancora nessun risultato",
    "emptyDescription": "Registra esami come HbA1c, LDL o ferritina per seguirli nel tempo e condividerli con il tuo medico.",
    "referenceLabel": "Riferimento",
-    "readingsCount": "{count} valori",
+    "readingsCount": "{count} misurazioni",
    "deleteLatest": "Elimina l'ultimo valore",
    "deleteConfirmTitle": "Eliminare il risultato di laboratorio?",
    "deleteConfirmDescription": "Questo risultato di laboratorio verrà eliminato definitivamente.",
@@ -6551,11 +6551,127 @@
      "referenceHint": "Copia l'intervallo di riferimento dal referto. Ciascun limite è facoltativo.",
      "note": "Nota",
      "notePlaceholder": "Contesto facoltativo per questo risultato",
-      "requiredError": "Biomarcatore, valore e unità sono obbligatori.",
+      "requiredError": "Inserisci un valore.",
      "rangeOrderError": "Il riferimento minimo non può superare quello massimo.",
      "save": "Salva",
      "savedToast": "Risultato salvato",
-      "saveError": "Impossibile salvare il risultato"
+      "saveError": "Impossibile salvare il risultato",
+      "biomarker": "Biomarcatore",
+      "biomarkerPlaceholder": "Scegli un biomarcatore",
+      "defineNew": "+ Definisci nuovo biomarcatore",
+      "noBiomarkersHint": "Definisci prima un biomarcatore per registrare un valore.",
+      "pickBiomarkerError": "Scegli prima un biomarcatore."
+    },
+    "backToLabs": "Torna ai risultati",
+    "hasNote": "Nota",
+    "editTitle": "Modifica misurazione",
+    "editDescription": "Correggi valore, data o nota di questa misurazione.",
+    "editedToast": "Misurazione aggiornata",
+    "editError": "Impossibile aggiornare la misurazione",
+    "editTimestampError": "Inserisci una data valida.",
+    "editReading": "Modifica misurazione",
+    "deleteReading": "Elimina misurazione",
+    "restoredToast": "Misurazione ripristinata",
+    "restoreError": "Impossibile ripristinare la misurazione",
+    "detail": {
+      "history": "Cronologia",
+      "emptyTitle": "Ancora nessuna misurazione",
+      "emptyDescription": "Aggiungi un valore per seguire questo biomarcatore nel tempo."
+    },
+    "chart": {
+      "empty": "Nessuna misurazione in questo periodo.",
+      "valueLabel": "Valore",
+      "range": {
+        "30": "30 g",
+        "90": "90 g",
+        "365": "1 a",
+        "all": "Tutto"
+      }
+    },
+    "biomarker": {
+      "manage": "Biomarcatori",
+      "manageTitle": "Biomarcatori",
+      "manageSheetDescription": "Definisci i marcatori che segui. Ognuno si imposta una volta con la sua unità e l'intervallo di riferimento.",
+      "managerDescription": "Definisci un marcatore una volta — unità e intervallo valgono per ogni misurazione.",
+      "define": "Definisci",
+      "defineFirst": "Definisci il tuo primo biomarcatore",
+      "defineTitle": "Definisci biomarcatore",
+      "defineDescription": "Imposta nome, unità e intervallo una volta. Scegli il marcatore quando aggiungi un valore.",
+      "editTitle": "Modifica biomarcatore",
+      "edit": "Modifica",
+      "delete": "Elimina",
+      "deletedToast": "Biomarcatore eliminato",
+      "deleteError": "Impossibile eliminare il biomarcatore",
+      "deleteConfirmTitle": "Eliminare il biomarcatore?",
+      "deleteConfirmDescription": "La definizione viene rimossa. Le misurazioni esistenti restano ma vengono scollegate.",
+      "emptyTitle": "Ancora nessun biomarcatore",
+      "emptyDescription": "Definisci marcatori come LDL o HbA1c per registrare i valori.",
+      "loadError": "Impossibile caricare i biomarcatori",
+      "noRange": "Nessun intervallo di riferimento",
+      "form": {
+        "seedLabel": "Parti da un marcatore comune",
+        "seedPlaceholder": "Scegli un marcatore (facoltativo)",
+        "seedHint": "Sceglierne uno compila i campi — adatta l'intervallo al tuo laboratorio.",
+        "name": "Nome",
+        "namePlaceholder": "es. Colesterolo LDL",
+        "unit": "Unità",
+        "unitPlaceholder": "es. mg/dL",
+        "panel": "Panel",
+        "panelPlaceholder": "es. Lipidi",
+        "lowerBound": "Riferimento minimo",
+        "upperBound": "Riferimento massimo",
+        "lowerPlaceholder": "Limite inferiore",
+        "upperPlaceholder": "Limite superiore",
+        "context": "Contesto",
+        "contextPlaceholder": "Nota facoltativa su questo marcatore",
+        "rangeHint": "Entrambi i limiti sono facoltativi — lasciane uno vuoto per un intervallo aperto (es. LDL < 116).",
+        "requiredError": "Nome e unità sono obbligatori.",
+        "rangeOrderError": "Il limite inferiore non deve superare quello superiore.",
+        "save": "Salva biomarcatore",
+        "savedToast": "Biomarcatore salvato",
+        "updatedToast": "Biomarcatore aggiornato",
+        "saveError": "Impossibile salvare il biomarcatore"
+      }
+    },
+    "catalog": {
+      "total-cholesterol": "Colesterolo totale",
+      "ldl": "Colesterolo LDL",
+      "hdl": "Colesterolo HDL",
+      "triglycerides": "Trigliceridi",
+      "fasting-glucose": "Glicemia a digiuno",
+      "hba1c": "HbA1c",
+      "tsh": "TSH",
+      "ft3": "T3 libero",
+      "ft4": "T4 libero",
+      "ferritin": "Ferritina",
+      "transferrin-saturation": "Saturazione della transferrina",
+      "vitamin-d": "Vitamina D (25-OH)",
+      "vitamin-b12": "Vitamina B12",
+      "folate": "Folati",
+      "hs-crp": "PCR ad alta sensibilità",
+      "creatinine": "Creatinina",
+      "egfr": "eGFR",
+      "alt": "ALT",
+      "ast": "AST",
+      "ggt": "GGT",
+      "sodium": "Sodio",
+      "potassium": "Potassio",
+      "hemoglobin": "Emoglobina",
+      "hematocrit": "Ematocrito",
+      "wbc": "Leucociti",
+      "platelets": "Piastrine",
+      "panel": {
+        "lipids": "Lipidi",
+        "glucose": "Metabolismo del glucosio",
+        "thyroid": "Tiroide",
+        "iron": "Ferro",
+        "vitamins": "Vitamine",
+        "inflammation": "Infiammazione",
+        "renal": "Reni",
+        "liver": "Fegato",
+        "electrolytes": "Elettroliti",
+        "bloodCount": "Emocromo"
+      }
    }
  },
  "modules": {
@@ -6516,13 +6516,13 @@
  "labs": {
    "title": "Wyniki badań",
    "subtitle": "Badania krwi i biomarkery",
-    "addResult": "Dodaj",
+    "addResult": "Dodaj wynik",
    "addDescription": "Zapisz biomarker z wyniku laboratoryjnego.",
    "addFirst": "Dodaj pierwszy wynik",
    "emptyTitle": "Brak wyników badań",
    "emptyDescription": "Zapisuj badania takie jak HbA1c, LDL czy ferrytyna, aby śledzić je w czasie i udostępniać lekarzowi.",
    "referenceLabel": "Norma",
-    "readingsCount": "{count} wyników",
+    "readingsCount": "{count} pomiarów",
    "deleteLatest": "Usuń ostatni wynik",
    "deleteConfirmTitle": "Usunąć wynik laboratoryjny?",
    "deleteConfirmDescription": "Ten wynik laboratoryjny zostanie trwale usunięty.",
@@ -6551,11 +6551,127 @@
      "referenceHint": "Przepisz zakres referencyjny z wyniku laboratoryjnego. Każda z granic jest opcjonalna.",
      "note": "Notatka",
      "notePlaceholder": "Opcjonalny kontekst tego wyniku",
-      "requiredError": "Biomarker, wartość i jednostka są wymagane.",
+      "requiredError": "Podaj wartość.",
      "rangeOrderError": "Norma dolna nie może przekraczać górnej.",
      "save": "Zapisz",
      "savedToast": "Wynik zapisany",
-      "saveError": "Nie udało się zapisać wyniku"
+      "saveError": "Nie udało się zapisać wyniku",
+      "biomarker": "Biomarker",
+      "biomarkerPlaceholder": "Wybierz biomarker",
+      "defineNew": "+ Zdefiniuj nowy biomarker",
+      "noBiomarkersHint": "Najpierw zdefiniuj biomarker, aby zapisać wartość.",
+      "pickBiomarkerError": "Najpierw wybierz biomarker."
+    },
+    "backToLabs": "Wróć do wyników",
+    "hasNote": "Notatka",
+    "editTitle": "Edytuj pomiar",
+    "editDescription": "Popraw wartość, datę lub notatkę tego pomiaru.",
+    "editedToast": "Pomiar zaktualizowany",
+    "editError": "Nie udało się zaktualizować pomiaru",
+    "editTimestampError": "Podaj prawidłową datę.",
+    "editReading": "Edytuj pomiar",
+    "deleteReading": "Usuń pomiar",
+    "restoredToast": "Pomiar przywrócony",
+    "restoreError": "Nie udało się przywrócić pomiaru",
+    "detail": {
+      "history": "Historia",
+      "emptyTitle": "Brak pomiarów",
+      "emptyDescription": "Dodaj wartość, aby śledzić ten biomarker w czasie."
+    },
+    "chart": {
+      "empty": "Brak pomiarów w tym okresie.",
+      "valueLabel": "Wartość",
+      "range": {
+        "30": "30 d",
+        "90": "90 d",
+        "365": "1 r",
+        "all": "Wszystko"
+      }
+    },
+    "biomarker": {
+      "manage": "Biomarkery",
+      "manageTitle": "Biomarkery",
+      "manageSheetDescription": "Zdefiniuj śledzone markery. Każdy ustawiasz raz wraz z jednostką i zakresem referencyjnym.",
+      "managerDescription": "Zdefiniuj marker raz — jednostka i zakres są używane dla każdego pomiaru.",
+      "define": "Zdefiniuj",
+      "defineFirst": "Zdefiniuj pierwszy biomarker",
+      "defineTitle": "Zdefiniuj biomarker",
+      "defineDescription": "Ustaw nazwę, jednostkę i zakres raz. Marker wybierasz przy dodawaniu wartości.",
+      "editTitle": "Edytuj biomarker",
+      "edit": "Edytuj",
+      "delete": "Usuń",
+      "deletedToast": "Biomarker usunięty",
+      "deleteError": "Nie udało się usunąć biomarkera",
+      "deleteConfirmTitle": "Usunąć biomarker?",
+      "deleteConfirmDescription": "Definicja zostanie usunięta. Istniejące pomiary pozostaną, ale bez powiązania.",
+      "emptyTitle": "Brak biomarkerów",
+      "emptyDescription": "Zdefiniuj markery, takie jak LDL lub HbA1c, aby zapisywać wartości.",
+      "loadError": "Nie udało się wczytać biomarkerów",
+      "noRange": "Brak zakresu referencyjnego",
+      "form": {
+        "seedLabel": "Zacznij od popularnego markera",
+        "seedPlaceholder": "Wybierz marker (opcjonalnie)",
+        "seedHint": "Wybór wypełnia pola poniżej — dopasuj zakres do swojego laboratorium.",
+        "name": "Nazwa",
+        "namePlaceholder": "np. Cholesterol LDL",
+        "unit": "Jednostka",
+        "unitPlaceholder": "np. mg/dl",
+        "panel": "Panel",
+        "panelPlaceholder": "np. Lipidy",
+        "lowerBound": "Dolna granica",
+        "upperBound": "Górna granica",
+        "lowerPlaceholder": "Dolna granica",
+        "upperPlaceholder": "Górna granica",
+        "context": "Kontekst",
+        "contextPlaceholder": "Opcjonalna notatka o tym markerze",
+        "rangeHint": "Obie granice są opcjonalne — zostaw jedną pustą dla zakresu otwartego (np. LDL < 116).",
+        "requiredError": "Nazwa i jednostka są wymagane.",
+        "rangeOrderError": "Dolna granica nie może przekraczać górnej.",
+        "save": "Zapisz biomarker",
+        "savedToast": "Biomarker zapisany",
+        "updatedToast": "Biomarker zaktualizowany",
+        "saveError": "Nie udało się zapisać biomarkera"
+      }
+    },
+    "catalog": {
+      "total-cholesterol": "Cholesterol całkowity",
+      "ldl": "Cholesterol LDL",
+      "hdl": "Cholesterol HDL",
+      "triglycerides": "Trójglicerydy",
+      "fasting-glucose": "Glukoza na czczo",
+      "hba1c": "HbA1c",
+      "tsh": "TSH",
+      "ft3": "Wolne T3",
+      "ft4": "Wolne T4",
+      "ferritin": "Ferrytyna",
+      "transferrin-saturation": "Wysycenie transferyny",
+      "vitamin-d": "Witamina D (25-OH)",
+      "vitamin-b12": "Witamina B12",
+      "folate": "Kwas foliowy",
+      "hs-crp": "hs-CRP",
+      "creatinine": "Kreatynina",
+      "egfr": "eGFR",
+      "alt": "ALT",
+      "ast": "AST",
+      "ggt": "GGTP",
+      "sodium": "Sód",
+      "potassium": "Potas",
+      "hemoglobin": "Hemoglobina",
+      "hematocrit": "Hematokryt",
+      "wbc": "Leukocyty",
+      "platelets": "Płytki krwi",
+      "panel": {
+        "lipids": "Lipidy",
+        "glucose": "Metabolizm glukozy",
+        "thyroid": "Tarczyca",
+        "iron": "Żelazo",
+        "vitamins": "Witaminy",
+        "inflammation": "Stan zapalny",
+        "renal": "Nerki",
+        "liver": "Wątroba",
+        "electrolytes": "Elektrolity",
+        "bloodCount": "Morfologia krwi"
+      }
    }
  },
  "modules": {
@@ -74,6 +74,8 @@ const MODULE_ROUTE_TREES: ReadonlyArray<string> = [
  "src/app/api/sleep",
  "src/app/api/workouts",
  "src/app/api/labs",
+  // v1.18.1 — the user-scoped Biomarker catalog backs the Labs feature.
+  "src/app/api/biomarkers",
  "src/app/api/cycle",
  "src/app/api/gamification",
  // v1.18.0 B3 — the legacy `/api/doctor-report` tree (JSON + server-PDF +
@@ -129,6 +131,14 @@ const EXEMPT_ROUTES: ReadonlyArray<string> = [
  "src/app/api/workouts/batch/route.ts",
  "src/app/api/labs/route.ts",
  "src/app/api/labs/[id]/route.ts",
+  // v1.18.1 — the lab-result delete-Undo restore endpoint and the
+  // user-scoped Biomarker catalog CRUD share the LabResult data-layer
+  // reasoning: the labs module gates the SURFACES (the Labs page), not the
+  // row store. A synced / pre-existing reading and its catalog definition
+  // must survive a disabled module so re-enabling reveals a complete history.
+  "src/app/api/labs/restore/route.ts",
+  "src/app/api/biomarkers/route.ts",
+  "src/app/api/biomarkers/[id]/route.ts",
  // ── INFRA / UI-ONLY ───────────────────────────────────────────────
  // Static FHIR CapabilityStatement — server metadata, no user data.
  "src/app/api/fhir/metadata/route.ts",
@@ -0,0 +1,190 @@
+import { NextRequest } from "next/server";
+
+import { apiHandler, requireAuth } from "@/lib/api-handler";
+import {
+  apiError,
+  apiSuccess,
+  getClientIp,
+  returnAllZodIssues,
+  safeJson,
+  sanitiseZodIssues,
+} from "@/lib/api-response";
+import { auditLog } from "@/lib/auth/audit";
+import { prisma } from "@/lib/db";
+import {
+  decryptContextFromBytes,
+  encryptContextToBytes,
+} from "@/lib/labs/biomarker-store";
+import { annotate } from "@/lib/logging/context";
+import { updateBiomarkerSchema } from "@/lib/validations/biomarkers";
+
+/**
+ * v1.18.1 — single Biomarker resource (`/api/biomarkers/{id}`).
+ *
+ * PUT applies a partial edit (`data` built field-by-field; an explicit `null`
+ * clears `context` / `panel` / a bound, an omitted key leaves it untouched).
+ * DELETE hard-deletes the catalog definition — the `onDelete: SetNull` FK on
+ * `LabResult.biomarkerId` unlinks every reading without losing it (the row
+ * keeps its legacy `analyte` / `unit` historical fields). Cross-user rows
+ * surface as 404 (existence sealed).
+ */
+
+type RouteParams = { params: Promise<{ id: string }> };
+
+function serialiseBiomarker(row: {
+  id: string;
+  name: string;
+  unit: string;
+  lowerBound: number | null;
+  upperBound: number | null;
+  panel: string | null;
+  contextEncrypted: Uint8Array | null;
+  createdAt: Date;
+  updatedAt: Date;
+}) {
+  return {
+    id: row.id,
+    name: row.name,
+    unit: row.unit,
+    lowerBound: row.lowerBound,
+    upperBound: row.upperBound,
+    panel: row.panel,
+    hasContext: row.contextEncrypted !== null,
+    context: row.contextEncrypted
+      ? decryptContextFromBytes(row.contextEncrypted)
+      : null,
+    createdAt: row.createdAt.toISOString(),
+    updatedAt: row.updatedAt.toISOString(),
+  };
+}
+
+export const GET = apiHandler(
+  async (_request: NextRequest, { params }: RouteParams) => {
+    const { user } = await requireAuth();
+    const { id } = await params;
+
+    const row = await prisma.biomarker.findFirst({ where: { id } });
+    if (!row || row.userId !== user.id) {
+      return apiError("Biomarker not found", 404);
+    }
+
+    annotate({
+      action: { name: "labs.biomarker.get" },
+      meta: { biomarkerId: id },
+    });
+
+    return apiSuccess(serialiseBiomarker(row));
+  },
+);
+
+export const PUT = apiHandler(
+  async (request: NextRequest, { params }: RouteParams) => {
+    const { user } = await requireAuth();
+    const { id } = await params;
+
+    const existing = await prisma.biomarker.findFirst({ where: { id } });
+    if (!existing || existing.userId !== user.id) {
+      return apiError("Biomarker not found", 404);
+    }
+
+    const { data: body, error: jsonError } = await safeJson(request, {
+      maxBytes: 16 * 1024,
+    });
+    if (jsonError) return jsonError;
+
+    const parsed = updateBiomarkerSchema.safeParse(body);
+    if (!parsed.success) {
+      annotate({
+        action: { name: "labs.biomarker.update.validation-failed" },
+        meta: { issue_count: parsed.error.issues.length, biomarkerId: id },
+      });
+      const auditIssues = sanitiseZodIssues(parsed.error.issues, {
+        stripValuesFromMessage: true,
+      });
+      prisma.auditLog
+        .create({
+          data: {
+            userId: user.id,
+            action: "labs.biomarker.update.validation-failed",
+            details: JSON.stringify({ issues: auditIssues, biomarkerId: id }),
+          },
+        })
+        .catch(() => {
+          /* swallow — the 422 response is the contract */
+        });
+      return returnAllZodIssues(parsed.error, 422);
+    }
+
+    const d = parsed.data;
+
+    // A rename must not collide with another of the caller's markers.
+    if (d.name !== undefined && d.name !== existing.name) {
+      const clash = await prisma.biomarker.findFirst({
+        where: { userId: user.id, name: d.name },
+        select: { id: true },
+      });
+      if (clash) {
+        return apiError("A biomarker with this name already exists", 409);
+      }
+    }
+
+    // Build `data` field-by-field. `undefined` → leave the column untouched;
+    // an explicit `null` on `context` / `panel` / a bound clears it.
+    const data: Record<string, unknown> = {};
+    if (d.name !== undefined) data.name = d.name;
+    if (d.unit !== undefined) data.unit = d.unit;
+    if (d.lowerBound !== undefined) data.lowerBound = d.lowerBound;
+    if (d.upperBound !== undefined) data.upperBound = d.upperBound;
+    if (d.panel !== undefined) data.panel = d.panel;
+    if (d.context !== undefined) {
+      data.contextEncrypted = d.context
+        ? encryptContextToBytes(d.context)
+        : null;
+    }
+
+    const updated = await prisma.biomarker.update({ where: { id }, data });
+
+    await auditLog("biomarker.update", {
+      userId: user.id,
+      ipAddress: getClientIp(request),
+      details: { biomarkerId: id },
+    });
+
+    annotate({
+      action: { name: "labs.biomarker.update" },
+      meta: { biomarkerId: id },
+    });
+
+    return apiSuccess(serialiseBiomarker(updated));
+  },
+);
+
+export const DELETE = apiHandler(
+  async (request: NextRequest, { params }: RouteParams) => {
+    const { user } = await requireAuth();
+    const { id } = await params;
+
+    const existing = await prisma.biomarker.findFirst({ where: { id } });
+    if (!existing || existing.userId !== user.id) {
+      return apiError("Biomarker not found", 404);
+    }
+
+    // Hard delete — the `onDelete: SetNull` FK unlinks every reading rather
+    // than cascading it away. The readings keep their legacy `analyte` /
+    // `unit` so the history survives the catalog edit.
+    await prisma.biomarker.delete({ where: { id } });
+
+    await auditLog("biomarker.delete", {
+      userId: user.id,
+      ipAddress: getClientIp(request),
+      details: { biomarkerId: id },
+    });
+
+    annotate({
+      action: { name: "labs.biomarker.delete" },
+      meta: { biomarkerId: id },
+    });
+
+    return apiSuccess({ deleted: true });
+  },
+);
@@ -0,0 +1,151 @@
+import { NextRequest } from "next/server";
+
+import { apiHandler, requireAuth } from "@/lib/api-handler";
+import {
+  apiError,
+  apiSuccess,
+  getClientIp,
+  returnAllZodIssues,
+  safeJson,
+  sanitiseZodIssues,
+} from "@/lib/api-response";
+import { auditLog } from "@/lib/auth/audit";
+import { prisma } from "@/lib/db";
+import { withIdempotency } from "@/lib/idempotency";
+import {
+  decryptContextFromBytes,
+  encryptContextToBytes,
+} from "@/lib/labs/biomarker-store";
+import { annotate } from "@/lib/logging/context";
+import { createBiomarkerSchema } from "@/lib/validations/biomarkers";
+
+/**
+ * v1.18.1 — user-scoped Biomarker catalog (`/api/biomarkers`).
+ *
+ * The catalog is the Labs feature's primary object: a marker is defined ONCE
+ * (name, unit, reference bounds, optional context) and every later reading
+ * just picks it. GET lists the caller's markers; POST defines a new one.
+ * `userId` is always narrowed from the session — never a body field — and the
+ * write `data` object is built field-by-field (no mass assignment). The
+ * optional context note is AES-256-GCM encrypted into the `contextEncrypted`
+ * Bytes column before write. The `@@unique([userId, name])` index means there
+ * is never a second "LDL" definition for one user.
+ */
+
+// The encrypted context bytes are never echoed back; `hasContext` flags
+// presence and the single-resource GET returns the decrypted text.
+function serialiseBiomarker(row: {
+  id: string;
+  name: string;
+  unit: string;
+  lowerBound: number | null;
+  upperBound: number | null;
+  panel: string | null;
+  contextEncrypted: Uint8Array | null;
+  createdAt: Date;
+  updatedAt: Date;
+}) {
+  return {
+    id: row.id,
+    name: row.name,
+    unit: row.unit,
+    lowerBound: row.lowerBound,
+    upperBound: row.upperBound,
+    panel: row.panel,
+    hasContext: row.contextEncrypted !== null,
+    context: row.contextEncrypted
+      ? decryptContextFromBytes(row.contextEncrypted)
+      : null,
+    createdAt: row.createdAt.toISOString(),
+    updatedAt: row.updatedAt.toISOString(),
+  };
+}
+
+export const GET = apiHandler(async () => {
+  const { user } = await requireAuth();
+
+  const rows = await prisma.biomarker.findMany({
+    where: { userId: user.id },
+    orderBy: [{ name: "asc" }],
+  });
+
+  annotate({
+    action: { name: "labs.biomarker.list" },
+    meta: { total: rows.length },
+  });
+
+  return apiSuccess({ biomarkers: rows.map(serialiseBiomarker) });
+});
+
+export const POST = apiHandler(withIdempotency<[NextRequest]>(postBiomarker));
+
+async function postBiomarker(request: NextRequest) {
+  const { user } = await requireAuth();
+
+  const { data: body, error: jsonError } = await safeJson(request, {
+    maxBytes: 16 * 1024,
+  });
+  if (jsonError) return jsonError;
+
+  const parsed = createBiomarkerSchema.safeParse(body);
+  if (!parsed.success) {
+    annotate({
+      action: { name: "labs.biomarker.create.validation-failed" },
+      meta: { issue_count: parsed.error.issues.length },
+    });
+    const auditIssues = sanitiseZodIssues(parsed.error.issues, {
+      stripValuesFromMessage: true,
+    });
+    prisma.auditLog
+      .create({
+        data: {
+          userId: user.id,
+          action: "labs.biomarker.create.validation-failed",
+          details: JSON.stringify({ issues: auditIssues }),
+        },
+      })
+      .catch(() => {
+        /* swallow — the 422 response is the contract */
+      });
+    return returnAllZodIssues(parsed.error, 422);
+  }
+
+  const { name, unit, lowerBound, upperBound, context, panel } = parsed.data;
+
+  // Reject a duplicate name up front so the client sees a clean 409 rather
+  // than a Prisma unique-constraint 500. The `@@unique([userId, name])` index
+  // is the structural backstop.
+  const existing = await prisma.biomarker.findFirst({
+    where: { userId: user.id, name },
+    select: { id: true },
+  });
+  if (existing) {
+    return apiError("A biomarker with this name already exists", 409);
+  }
+
+  // Field-by-field assignment — never spread `parsed.data`.
+  const created = await prisma.biomarker.create({
+    data: {
+      userId: user.id,
+      name,
+      unit,
+      lowerBound: lowerBound ?? null,
+      upperBound: upperBound ?? null,
+      panel: panel ?? null,
+      contextEncrypted: context ? encryptContextToBytes(context) : null,
+    },
+  });
+
+  await auditLog("biomarker.create", {
+    userId: user.id,
+    ipAddress: getClientIp(request),
+    details: { biomarkerId: created.id },
+  });
+
+  annotate({
+    action: { name: "labs.biomarker.create" },
+    meta: { biomarkerId: created.id },
+  });
+
+  return apiSuccess(serialiseBiomarker(created), 201);
+}
@@ -11,12 +11,14 @@ import {
 } from "@/lib/api-response";
 import { auditLog } from "@/lib/auth/audit";
 import { prisma } from "@/lib/db";
+import {
+  type ResolvedBiomarker,
+  serialiseLabResult,
+  serialiseLabResultDetail,
+} from "@/lib/labs/serialise";
 import { decryptNoteFromBytes, encryptNoteToBytes } from "@/lib/labs/store";
 import { annotate } from "@/lib/logging/context";
-import {
-  classifyReferenceRange,
-  updateLabResultSchema,
-} from "@/lib/validations/labs";
+import { updateLabResultSchema } from "@/lib/validations/labs";

 /**
 * v1.17.1 — single lab-result resource (`/api/labs/{id}`).
@@ -26,10 +28,36 @@ import {
 * (`data` built field-by-field; an explicit `null` clears `panel` / `note` /
 * a reference bound, an omitted key leaves it untouched). DELETE soft-deletes
 * by stamping `deletedAt`. Cross-user rows surface as 404 (existence sealed).
+ *
+ * v1.18.1 — when the row links a `Biomarker`, the response resolves the
+ * canonical name / unit / range from the catalog (server-authoritative). The
+ * legacy per-row free-text fields stay editable for an unlinked row.
 */

 type RouteParams = { params: Promise<{ id: string }> };

+const biomarkerSelect = {
+  id: true,
+  name: true,
+  unit: true,
+  lowerBound: true,
+  upperBound: true,
+  panel: true,
+} as const;
+
+function toResolved(
+  bm: {
+    id: string;
+    name: string;
+    unit: string;
+    lowerBound: number | null;
+    upperBound: number | null;
+    panel: string | null;
+  } | null,
+): ResolvedBiomarker | null {
+  return bm ?? null;
+}
+
 export const GET = apiHandler(
  async (_request: NextRequest, { params }: RouteParams) => {
    const { user } = await requireAuth();
@@ -37,6 +65,7 @@ export const GET = apiHandler(

    const row = await prisma.labResult.findFirst({
      where: { id, deletedAt: null },
+      include: { biomarker: { select: biomarkerSelect } },
    });
    if (!row || row.userId !== user.id) {
      return apiError("Lab result not found", 404);
@@ -44,27 +73,13 @@ export const GET = apiHandler(

    annotate({ action: { name: "labs.get" }, meta: { labResultId: id } });

-    return apiSuccess({
-      id: row.id,
-      panel: row.panel,
-      analyte: row.analyte,
-      value: row.value,
-      unit: row.unit,
-      referenceLow: row.referenceLow,
-      referenceHigh: row.referenceHigh,
-      takenAt: row.takenAt.toISOString(),
-      source: row.source,
-      note: row.noteEncrypted
-        ? decryptNoteFromBytes(row.noteEncrypted)
-        : null,
-      rangeStatus: classifyReferenceRange(
-        row.value,
-        row.referenceLow,
-        row.referenceHigh,
+    return apiSuccess(
+      serialiseLabResultDetail(
+        row,
+        toResolved(row.biomarker),
+        row.noteEncrypted ? decryptNoteFromBytes(row.noteEncrypted) : null,
      ),
-      createdAt: row.createdAt.toISOString(),
-      updatedAt: row.updatedAt.toISOString(),
-    });
+    );
  },
 );

@@ -112,6 +127,8 @@ export const PUT = apiHandler(

    // Build `data` field-by-field. `undefined` → leave the column untouched;
    // an explicit `null` on `panel` / `note` / a reference bound clears it.
+    // A reading linked to a catalog marker is edited via VALUE / takenAt /
+    // note here; its name / unit / range stay resolved from the biomarker.
    const data: Record<string, unknown> = {};
    if (d.panel !== undefined) data.panel = d.panel;
    if (d.analyte !== undefined) data.analyte = d.analyte;
@@ -124,7 +141,11 @@ export const PUT = apiHandler(
      data.noteEncrypted = d.note ? encryptNoteToBytes(d.note) : null;
    }

-    const updated = await prisma.labResult.update({ where: { id }, data });
+    const updated = await prisma.labResult.update({
+      where: { id },
+      data,
+      include: { biomarker: { select: biomarkerSelect } },
+    });

    await auditLog("labResult.update", {
      userId: user.id,
@@ -134,25 +155,9 @@ export const PUT = apiHandler(

    annotate({ action: { name: "labs.update" }, meta: { labResultId: id } });

-    return apiSuccess({
-      id: updated.id,
-      panel: updated.panel,
-      analyte: updated.analyte,
-      value: updated.value,
-      unit: updated.unit,
-      referenceLow: updated.referenceLow,
-      referenceHigh: updated.referenceHigh,
-      takenAt: updated.takenAt.toISOString(),
-      source: updated.source,
-      hasNote: updated.noteEncrypted !== null,
-      rangeStatus: classifyReferenceRange(
-        updated.value,
-        updated.referenceLow,
-        updated.referenceHigh,
-      ),
-      createdAt: updated.createdAt.toISOString(),
-      updatedAt: updated.updatedAt.toISOString(),
-    });
+    return apiSuccess(
+      serialiseLabResult(updated, toResolved(updated.biomarker)),
+    );
  },
 );

@@ -178,7 +183,7 @@ export const DELETE = apiHandler(
    await auditLog("labResult.delete", {
      userId: user.id,
      ipAddress: getClientIp(request),
-      details: { labResultId: id, analyte: existing.analyte },
+      details: { labResultId: id },
    });

    annotate({ action: { name: "labs.delete" }, meta: { labResultId: id } });
@@ -0,0 +1,73 @@
+/**
+ * `POST /api/labs/restore` — un-tombstone for the lab-history delete-Undo
+ * affordance (v1.18.1).
+ *
+ * Body: `{ ids: string[] }` — 1..200 lab-result ids, scoped to the caller.
+ *
+ * Clears `deletedAt` on every owned, currently-tombstoned row in one
+ * `updateMany`, so the reading re-surfaces in normal reads. A forged /
+ * foreign / not-deleted id is a silent no-op (never a 404 existence leak):
+ * the mutation `where` pins `userId` so it only ever touches the caller's
+ * rows. Mirrors `/api/measurements/restore`.
+ */
+import { NextRequest } from "next/server";
+import { z } from "zod/v4";
+
+import { apiHandler, requireAuth } from "@/lib/api-handler";
+import {
+  apiError,
+  apiSuccess,
+  returnAllZodIssues,
+  safeJson,
+} from "@/lib/api-response";
+import { prisma } from "@/lib/db";
+import { withIdempotency } from "@/lib/idempotency";
+import { annotate } from "@/lib/logging/context";
+import { checkRateLimit } from "@/lib/rate-limit";
+
+const MAX_IDS_PER_BATCH = 200;
+const RATE_LIMIT_MAX = 60;
+const RATE_LIMIT_WINDOW_MS = 60 * 1000;
+
+const restoreSchema = z.object({
+  ids: z.array(z.string().min(1)).min(1).max(MAX_IDS_PER_BATCH),
+});
+
+export const POST = apiHandler(withIdempotency<[NextRequest]>(postRestore));
+
+async function postRestore(request: NextRequest): Promise<Response> {
+  const { user } = await requireAuth();
+
+  const rl = await checkRateLimit(
+    `labs:restore:${user.id}`,
+    RATE_LIMIT_MAX,
+    RATE_LIMIT_WINDOW_MS,
+  );
+  if (!rl.allowed) {
+    return apiError("Too many restore requests, try again later", 429);
+  }
+
+  const { data: rawBody, error: jsonError } = await safeJson(request, {
+    maxBytes: 64 * 1024,
+  });
+  if (jsonError) return jsonError;
+
+  const parsed = restoreSchema.safeParse(rawBody);
+  if (!parsed.success) {
+    return returnAllZodIssues(parsed.error, 422, {
+      errorCode: "labs.restore.invalid",
+    });
+  }
+
+  const { ids } = parsed.data;
+
+  // `userId`-scoped + `deletedAt != null`: a foreign / live id is skipped.
+  const { count } = await prisma.labResult.updateMany({
+    where: { id: { in: ids }, userId: user.id, deletedAt: { not: null } },
+    data: { deletedAt: null },
+  });
+
+  annotate({ action: { name: "labs.restore" }, meta: { restored: count } });
+
+  return apiSuccess({ restored: count });
+}
@@ -2,6 +2,7 @@ import { NextRequest } from "next/server";

 import { apiHandler, requireAuth } from "@/lib/api-handler";
 import {
+  apiError,
  apiSuccess,
  getClientIp,
  returnAllZodIssues,
@@ -12,10 +13,13 @@ import { auditLog } from "@/lib/auth/audit";
 import { prisma } from "@/lib/db";
 import { withIdempotency } from "@/lib/idempotency";
 import { enqueueReminderSatisfy } from "@/lib/jobs/reminder-satisfy";
+import {
+  type ResolvedBiomarker,
+  serialiseLabResult,
+} from "@/lib/labs/serialise";
 import { encryptNoteToBytes } from "@/lib/labs/store";
 import { annotate } from "@/lib/logging/context";
 import {
-  classifyReferenceRange,
  createLabResultSchema,
  listLabResultsSchema,
 } from "@/lib/validations/labs";
@@ -23,49 +27,31 @@ import {
 /**
 * v1.17.1 — structured lab-result store (`/api/labs`).
 *
- * GET lists the caller's live results with optional analyte / panel / date
- * filters. POST records a single reading. `userId` is always narrowed from
- * the session — never a body field — and the write `data` object is built
- * field-by-field (no mass assignment). The free-text note, when present, is
- * AES-256-GCM encrypted into the `noteEncrypted` Bytes column before write.
+ * GET lists the caller's live results with optional biomarker / analyte /
+ * panel / date filters. POST records a single reading. `userId` is always
+ * narrowed from the session — never a body field — and the write `data`
+ * object is built field-by-field (no mass assignment). The free-text note,
+ * when present, is AES-256-GCM encrypted into the `noteEncrypted` Bytes
+ * column before write.
+ *
+ * v1.18.1 — structured entry: when the body carries a `biomarkerId`, the row
+ * links the user-scoped catalog marker and the response resolves its unit +
+ * reference range FROM the biomarker (server-authoritative). The web + iOS
+ * clients render the resolved DTO and never recompute.
 */

-// The serialised row never echoes the encrypted note bytes back; the badge
-// status is computed server-side so the client renders a coherent, neutral
-// in/out-of-range verdict without re-deriving the rule.
-function serialiseLabResult(row: {
-  id: string;
-  panel: string | null;
-  analyte: string;
-  value: number;
-  unit: string;
-  referenceLow: number | null;
-  referenceHigh: number | null;
-  takenAt: Date;
-  source: string;
-  noteEncrypted: Uint8Array | null;
-  createdAt: Date;
-  updatedAt: Date;
-}) {
-  return {
-    id: row.id,
-    panel: row.panel,
-    analyte: row.analyte,
-    value: row.value,
-    unit: row.unit,
-    referenceLow: row.referenceLow,
-    referenceHigh: row.referenceHigh,
-    takenAt: row.takenAt.toISOString(),
-    source: row.source,
-    hasNote: row.noteEncrypted !== null,
-    rangeStatus: classifyReferenceRange(
-      row.value,
-      row.referenceLow,
-      row.referenceHigh,
-    ),
-    createdAt: row.createdAt.toISOString(),
-    updatedAt: row.updatedAt.toISOString(),
-  };
+/** Map the joined biomarker (or null) into the resolver's shape. */
+function toResolved(
+  bm: {
+    id: string;
+    name: string;
+    unit: string;
+    lowerBound: number | null;
+    upperBound: number | null;
+    panel: string | null;
+  } | null,
+): ResolvedBiomarker | null {
+  return bm ?? null;
 }

 export const GET = apiHandler(async (request: NextRequest) => {
@@ -81,11 +67,13 @@ export const GET = apiHandler(async (request: NextRequest) => {
    return returnAllZodIssues(parsed.error, 422);
  }

-  const { analyte, panel, from, to, limit, offset, sortDir } = parsed.data;
+  const { biomarkerId, analyte, panel, from, to, limit, offset, sortDir } =
+    parsed.data;

  const where = {
    userId: user.id,
    deletedAt: null,
+    ...(biomarkerId && { biomarkerId }),
    ...(analyte && { analyte }),
    ...(panel && { panel }),
    ...(from || to
@@ -104,6 +92,18 @@ export const GET = apiHandler(async (request: NextRequest) => {
      orderBy: { takenAt: sortDir },
      take: limit,
      skip: offset,
+      include: {
+        biomarker: {
+          select: {
+            id: true,
+            name: true,
+            unit: true,
+            lowerBound: true,
+            upperBound: true,
+            panel: true,
+          },
+        },
+      },
    }),
    prisma.labResult.count({ where }),
  ]);
@@ -114,7 +114,9 @@ export const GET = apiHandler(async (request: NextRequest) => {
  });

  return apiSuccess({
-    results: rows.map(serialiseLabResult),
+    results: rows.map((row) =>
+      serialiseLabResult(row, toResolved(row.biomarker)),
+    ),
    meta: { total, limit, offset },
  });
 });
@@ -154,20 +156,55 @@ async function postLabResult(request: NextRequest) {
    return returnAllZodIssues(parsed.error, 422);
  }

-  const { panel, analyte, value, unit, referenceLow, referenceHigh, takenAt, note } =
-    parsed.data;
+  const {
+    biomarkerId,
+    panel,
+    analyte,
+    value,
+    unit,
+    referenceLow,
+    referenceHigh,
+    takenAt,
+    note,
+  } = parsed.data;

-  // Field-by-field assignment — never spread `parsed.data`. `source` is
-  // hardcoded "MANUAL" for this user-facing path; import paths set their own.
+  // Structured-entry path: resolve the catalog marker (and verify ownership)
+  // so the row's name + unit derive from it. A forged / foreign id is a 404.
+  let biomarker: ResolvedBiomarker | null = null;
+  if (biomarkerId) {
+    const found = await prisma.biomarker.findFirst({
+      where: { id: biomarkerId, userId: user.id },
+      select: {
+        id: true,
+        name: true,
+        unit: true,
+        lowerBound: true,
+        upperBound: true,
+        panel: true,
+      },
+    });
+    if (!found) {
+      return apiError("Biomarker not found", 404);
+    }
+    biomarker = found;
+  }
+
+  // Field-by-field assignment — never spread `parsed.data`. With a catalog
+  // link the row stamps the resolved name/unit/range as historical truth
+  // (so a later catalog edit does not silently rewrite a past reading) AND
+  // keeps the FK; reads resolve the CURRENT catalog values via `serialise`.
  const created = await prisma.labResult.create({
    data: {
      userId: user.id,
-      panel: panel ?? null,
-      analyte,
+      biomarkerId: biomarker?.id ?? null,
+      panel: biomarker ? biomarker.panel : (panel ?? null),
+      analyte: biomarker ? biomarker.name : (analyte as string),
      value,
-      unit,
-      referenceLow: referenceLow ?? null,
-      referenceHigh: referenceHigh ?? null,
+      unit: biomarker ? biomarker.unit : (unit as string),
+      referenceLow: biomarker ? biomarker.lowerBound : (referenceLow ?? null),
+      referenceHigh: biomarker
+        ? biomarker.upperBound
+        : (referenceHigh ?? null),
      takenAt,
      source: "MANUAL",
      noteEncrypted: note ? encryptNoteToBytes(note) : null,
@@ -177,12 +214,12 @@ async function postLabResult(request: NextRequest) {
  await auditLog("labResult.create", {
    userId: user.id,
    ipAddress: getClientIp(request),
-    details: { labResultId: created.id, analyte: created.analyte },
+    details: { labResultId: created.id },
  });

  annotate({
    action: { name: "labs.create" },
-    meta: { labResultId: created.id },
+    meta: { labResultId: created.id, structured: biomarker !== null },
  });

  // v1.18.1 (D2) — eventful Lab↔Vorsorge satisfaction. A lab panel just
@@ -190,5 +227,5 @@ async function postLabResult(request: NextRequest) {
  // now rather than waiting on the 15-min cron. Fire-and-forget.
  void enqueueReminderSatisfy(user.id).catch(() => {});

-  return apiSuccess(serialiseLabResult(created), 201);
+  return apiSuccess(serialiseLabResult(created, biomarker), 201);
 }
@@ -0,0 +1,51 @@
+"use client";
+
+/**
+ * v1.18.1 — per-biomarker detail page (`/labs/[biomarkerId]`).
+ *
+ * Owns auth + the back link and hands the marker id to
+ * `<LabBiomarkerDetail>`, which carries the heading, the dashboard-style
+ * chart with the reference band, and the editable reading history.
+ */
+import { use, useEffect } from "react";
+import { useRouter } from "next/navigation";
+import { Loader2 } from "lucide-react";
+
+import { LabBiomarkerDetail } from "@/components/labs/lab-biomarker-detail";
+import { BackLink } from "@/components/ui/back-link";
+import { useAuth } from "@/hooks/use-auth";
+import { useMounted } from "@/hooks/use-mounted";
+import { useTranslations } from "@/lib/i18n/context";
+
+export default function LabBiomarkerDetailPage({
+  params,
+}: {
+  params: Promise<{ biomarkerId: string }>;
+}) {
+  const { biomarkerId } = use(params);
+  const { isAuthenticated, isLoading } = useAuth();
+  const mounted = useMounted();
+  const router = useRouter();
+  const { t } = useTranslations();
+
+  useEffect(() => {
+    if (!isLoading && !isAuthenticated) {
+      router.push("/auth/login");
+    }
+  }, [isLoading, isAuthenticated, router]);
+
+  if (!mounted || isLoading) {
+    return (
+      <div className="flex h-64 items-center justify-center">
+        <Loader2 className="text-primary h-8 w-8 animate-spin motion-reduce:animate-none" />
+      </div>
+    );
+  }
+
+  return (
+    <div className="space-y-6">
+      <BackLink href="/labs" label={t("labs.backToLabs")} />
+      <LabBiomarkerDetail biomarkerId={biomarkerId} />
+    </div>
+  );
+}
@@ -3,8 +3,9 @@
 import { useCallback, useEffect, useState } from "react";
 import { useRouter } from "next/navigation";
 import { useQueryClient } from "@tanstack/react-query";
-import { Loader2, Plus } from "lucide-react";
+import { FlaskConical, Loader2, Plus } from "lucide-react";

+import { BiomarkerManager } from "@/components/labs/biomarker-manager";
 import { LabForm } from "@/components/labs/lab-form";
 import { LabList } from "@/components/labs/lab-list";
 import { Button } from "@/components/ui/button";
@@ -23,6 +24,7 @@ export default function LabsPage() {
  const queryClient = useQueryClient();
  const { t } = useTranslations();
  const [dialogOpen, setDialogOpen] = useState(false);
+  const [manageOpen, setManageOpen] = useState(false);

  const refreshVisible = useCallback(
    () => queryClient.invalidateQueries({ type: "active" }),
@@ -30,7 +32,7 @@ export default function LabsPage() {
  );
  const pull = usePullToRefresh({
    onRefresh: refreshVisible,
-    disabled: dialogOpen,
+    disabled: dialogOpen || manageOpen,
  });

  useEffect(() => {
@@ -59,13 +61,25 @@ export default function LabsPage() {
            {t("labs.subtitle")}
          </p>
        </div>
-        <Button
-          onClick={() => setDialogOpen(true)}
-          className="min-h-11 shrink-0 sm:min-h-9"
-        >
-          <Plus className="h-4 w-4" />
-          {t("labs.addResult")}
-        </Button>
+        <div className="flex shrink-0 gap-2">
+          <Button
+            variant="outline"
+            onClick={() => setManageOpen(true)}
+            className="min-h-11 sm:min-h-9"
+          >
+            <FlaskConical className="h-4 w-4" />
+            <span className="hidden sm:inline">
+              {t("labs.biomarker.manage")}
+            </span>
+          </Button>
+          <Button
+            onClick={() => setDialogOpen(true)}
+            className="min-h-11 sm:min-h-9"
+          >
+            <Plus className="h-4 w-4" />
+            {t("labs.addResult")}
+          </Button>
+        </div>
      </div>

      <ResponsiveSheet
@@ -85,6 +99,15 @@ export default function LabsPage() {
        />
      </ResponsiveSheet>

+      <ResponsiveSheet
+        open={manageOpen}
+        onOpenChange={setManageOpen}
+        title={t("labs.biomarker.manageTitle")}
+        description={t("labs.biomarker.manageSheetDescription")}
+      >
+        <BiomarkerManager />
+      </ResponsiveSheet>
+
      <LabList onAddFirst={() => setDialogOpen(true)} />
    </div>
  );
@@ -0,0 +1,281 @@
+"use client";
+
+import { useState } from "react";
+import { Loader2 } from "lucide-react";
+import { toast } from "sonner";
+
+import { Button } from "@/components/ui/button";
+import { Input } from "@/components/ui/input";
+import { Label } from "@/components/ui/label";
+import {
+  Select,
+  SelectContent,
+  SelectGroup,
+  SelectItem,
+  SelectLabel,
+  SelectTrigger,
+  SelectValue,
+} from "@/components/ui/select";
+import { Textarea } from "@/components/ui/textarea";
+import { ApiError, apiPost, apiPut } from "@/lib/api/api-fetch";
+import {
+  BIOMARKER_CATALOG,
+  BIOMARKER_PANELS,
+} from "@/lib/labs/biomarker-catalog";
+import { useTranslations } from "@/lib/i18n/context";
+
+import type { BiomarkerDto } from "./types";
+
+const CONTEXT_MAX_LENGTH = 2000;
+
+/** Parse a free-text decimal that may use a comma separator. */
+function parseDecimal(raw: string): number | null {
+  const trimmed = raw.trim().replace(",", ".");
+  if (trimmed === "") return null;
+  const n = Number(trimmed);
+  return Number.isFinite(n) ? n : null;
+}
+
+interface BiomarkerFormProps {
+  /** When set the form edits this marker; otherwise it defines a new one. */
+  existing?: BiomarkerDto;
+  onSuccess?: (saved: BiomarkerDto) => void;
+  onCancel?: () => void;
+}
+
+/**
+ * v1.18.1 — define or edit a Biomarker catalog entry.
+ *
+ * A marker is the Labs feature's reusable definition: name, unit, reference
+ * bounds (set ONCE, never re-entered per reading), and an optional context
+ * note. When defining a new marker the user can seed the fields from the
+ * common-panel catalog (a `<Select>` grouped by panel) or fill them by hand.
+ * Either bound is optional (a marker may report only an upper bound, e.g.
+ * LDL < 116).
+ */
+export function BiomarkerForm({
+  existing,
+  onSuccess,
+  onCancel,
+}: BiomarkerFormProps) {
+  const { t } = useTranslations();
+
+  const [name, setName] = useState(existing?.name ?? "");
+  const [unit, setUnit] = useState(existing?.unit ?? "");
+  const [lower, setLower] = useState(
+    existing?.lowerBound != null ? String(existing.lowerBound) : "",
+  );
+  const [upper, setUpper] = useState(
+    existing?.upperBound != null ? String(existing.upperBound) : "",
+  );
+  const [panel, setPanel] = useState(existing?.panel ?? "");
+  const [context, setContext] = useState(existing?.context ?? "");
+  const [submitting, setSubmitting] = useState(false);
+  const [error, setError] = useState<string | null>(null);
+
+  function applySeed(slug: string) {
+    const seed = BIOMARKER_CATALOG.find((s) => s.slug === slug);
+    if (!seed) return;
+    setName(t(`labs.catalog.${seed.slug}`));
+    setUnit(seed.unit);
+    setLower(seed.lowerBound != null ? String(seed.lowerBound) : "");
+    setUpper(seed.upperBound != null ? String(seed.upperBound) : "");
+    setPanel(t(`labs.catalog.panel.${seed.panel}`));
+    setError(null);
+  }
+
+  async function handleSubmit(e: React.FormEvent) {
+    e.preventDefault();
+    setError(null);
+
+    if (!name.trim() || !unit.trim()) {
+      setError(t("labs.biomarker.form.requiredError"));
+      return;
+    }
+
+    const low = parseDecimal(lower);
+    const high = parseDecimal(upper);
+    if (low !== null && high !== null && low > high) {
+      setError(t("labs.biomarker.form.rangeOrderError"));
+      return;
+    }
+
+    const body = {
+      name: name.trim(),
+      unit: unit.trim(),
+      ...(low !== null ? { lowerBound: low } : {}),
+      ...(high !== null ? { upperBound: high } : {}),
+      ...(panel.trim() ? { panel: panel.trim() } : {}),
+      ...(context.trim() ? { context: context.trim() } : {}),
+    };
+
+    setSubmitting(true);
+    try {
+      const saved = existing
+        ? await apiPut<BiomarkerDto>(`/api/biomarkers/${existing.id}`, body)
+        : await apiPost<BiomarkerDto>("/api/biomarkers", body);
+      toast.success(
+        existing
+          ? t("labs.biomarker.form.updatedToast")
+          : t("labs.biomarker.form.savedToast"),
+      );
+      onSuccess?.(saved);
+    } catch (err) {
+      const message =
+        err instanceof ApiError ? err.message : t("labs.biomarker.form.saveError");
+      setError(message);
+    } finally {
+      setSubmitting(false);
+    }
+  }
+
+  return (
+    <form onSubmit={handleSubmit} className="space-y-5">
+      {!existing ? (
+        <div className="space-y-1.5">
+          <Label htmlFor="biomarker-seed">
+            {t("labs.biomarker.form.seedLabel")}
+          </Label>
+          <Select onValueChange={applySeed}>
+            <SelectTrigger id="biomarker-seed" className="w-full">
+              <SelectValue
+                placeholder={t("labs.biomarker.form.seedPlaceholder")}
+              />
+            </SelectTrigger>
+            <SelectContent>
+              {BIOMARKER_PANELS.map((panelKey) => {
+                const items = BIOMARKER_CATALOG.filter(
+                  (s) => s.panel === panelKey,
+                );
+                if (items.length === 0) return null;
+                return (
+                  <SelectGroup key={panelKey}>
+                    <SelectLabel>
+                      {t(`labs.catalog.panel.${panelKey}`)}
+                    </SelectLabel>
+                    {items.map((s) => (
+                      <SelectItem key={s.slug} value={s.slug}>
+                        {t(`labs.catalog.${s.slug}`)}
+                      </SelectItem>
+                    ))}
+                  </SelectGroup>
+                );
+              })}
+            </SelectContent>
+          </Select>
+          <p className="text-muted-foreground text-xs">
+            {t("labs.biomarker.form.seedHint")}
+          </p>
+        </div>
+      ) : null}
+
+      <div className="grid gap-4 sm:grid-cols-2">
+        <div className="space-y-1.5 sm:col-span-2">
+          <Label htmlFor="biomarker-name">
+            {t("labs.biomarker.form.name")}
+          </Label>
+          <Input
+            id="biomarker-name"
+            value={name}
+            onChange={(e) => setName(e.target.value)}
+            placeholder={t("labs.biomarker.form.namePlaceholder")}
+            maxLength={120}
+            autoFocus
+            required
+          />
+        </div>
+        <div className="space-y-1.5">
+          <Label htmlFor="biomarker-unit">
+            {t("labs.biomarker.form.unit")}
+          </Label>
+          <Input
+            id="biomarker-unit"
+            value={unit}
+            onChange={(e) => setUnit(e.target.value)}
+            placeholder={t("labs.biomarker.form.unitPlaceholder")}
+            maxLength={40}
+            required
+          />
+        </div>
+        <div className="space-y-1.5">
+          <Label htmlFor="biomarker-panel">
+            {t("labs.biomarker.form.panel")}
+          </Label>
+          <Input
+            id="biomarker-panel"
+            value={panel}
+            onChange={(e) => setPanel(e.target.value)}
+            placeholder={t("labs.biomarker.form.panelPlaceholder")}
+            maxLength={120}
+          />
+        </div>
+        <div className="space-y-1.5">
+          <Label htmlFor="biomarker-lower">
+            {t("labs.biomarker.form.lowerBound")}
+          </Label>
+          <Input
+            id="biomarker-lower"
+            inputMode="decimal"
+            value={lower}
+            onChange={(e) => setLower(e.target.value)}
+            placeholder={t("labs.biomarker.form.lowerPlaceholder")}
+          />
+        </div>
+        <div className="space-y-1.5">
+          <Label htmlFor="biomarker-upper">
+            {t("labs.biomarker.form.upperBound")}
+          </Label>
+          <Input
+            id="biomarker-upper"
+            inputMode="decimal"
+            value={upper}
+            onChange={(e) => setUpper(e.target.value)}
+            placeholder={t("labs.biomarker.form.upperPlaceholder")}
+          />
+        </div>
+        <div className="space-y-1.5 sm:col-span-2">
+          <Label htmlFor="biomarker-context">
+            {t("labs.biomarker.form.context")}
+          </Label>
+          <Textarea
+            id="biomarker-context"
+            value={context}
+            onChange={(e) => setContext(e.target.value)}
+            placeholder={t("labs.biomarker.form.contextPlaceholder")}
+            maxLength={CONTEXT_MAX_LENGTH}
+            rows={2}
+          />
+        </div>
+      </div>
+
+      <p className="text-muted-foreground text-xs">
+        {t("labs.biomarker.form.rangeHint")}
+      </p>
+
+      {error ? (
+        <p className="text-destructive text-sm" role="alert">
+          {error}
+        </p>
+      ) : null}
+
+      <div className="flex justify-end gap-2">
+        {onCancel ? (
+          <Button
+            type="button"
+            variant="ghost"
+            onClick={onCancel}
+            disabled={submitting}
+          >
+            {t("common.cancel")}
+          </Button>
+        ) : null}
+        <Button type="submit" disabled={submitting}>
+          {submitting ? (
+            <Loader2 className="h-4 w-4 animate-spin motion-reduce:animate-none" />
+          ) : null}
+          {t("labs.biomarker.form.save")}
+        </Button>
+      </div>
+    </form>
+  );
+}
@@ -0,0 +1,177 @@
+"use client";
+
+import { useState } from "react";
+import { useMutation, useQuery, useQueryClient } from "@tanstack/react-query";
+import { FlaskConical, Pencil, Plus } from "lucide-react";
+import { toast } from "sonner";
+
+import { DeleteButton } from "@/components/data-list";
+import { Button } from "@/components/ui/button";
+import { Card, CardContent } from "@/components/ui/card";
+import { EmptyState } from "@/components/ui/empty-state";
+import { ResponsiveSheet } from "@/components/ui/responsive-sheet";
+import { Skeleton } from "@/components/ui/skeleton";
+import { apiDelete, apiGet } from "@/lib/api/api-fetch";
+import { formatReferenceRange } from "@/lib/labs/reference-range";
+import { formatLabValue } from "@/lib/labs/format-value";
+import { useTranslations } from "@/lib/i18n/context";
+import { queryKeys } from "@/lib/query-keys";
+
+import { BiomarkerForm } from "./biomarker-form";
+import type { BiomarkerDto, BiomarkerListResponse } from "./types";
+
+/**
+ * v1.18.1 — the Biomarker catalog manager.
+ *
+ * Lives on the Labs page (not Settings) because the catalog IS the Labs
+ * feature's primary object. Lists every defined marker with its unit +
+ * reference range, opens a define-new / edit sheet, and wires delete (the
+ * `onDelete: SetNull` FK keeps existing readings, just unlinks them).
+ */
+export function BiomarkerManager() {
+  const { t } = useTranslations();
+  const queryClient = useQueryClient();
+  const [formOpen, setFormOpen] = useState(false);
+  const [editing, setEditing] = useState<BiomarkerDto | null>(null);
+
+  const { data, isLoading, isError } = useQuery({
+    queryKey: queryKeys.biomarkers(),
+    queryFn: () => apiGet<BiomarkerListResponse>("/api/biomarkers"),
+  });
+
+  const deleteMutation = useMutation({
+    mutationFn: (id: string) => apiDelete(`/api/biomarkers/${id}`),
+    onSuccess: () => {
+      toast.success(t("labs.biomarker.deletedToast"));
+      queryClient.invalidateQueries({ queryKey: queryKeys.biomarkers() });
+      queryClient.invalidateQueries({ queryKey: queryKeys.labResults() });
+    },
+    onError: () => toast.error(t("labs.biomarker.deleteError")),
+  });
+
+  function openNew() {
+    setEditing(null);
+    setFormOpen(true);
+  }
+
+  function openEdit(marker: BiomarkerDto) {
+    setEditing(marker);
+    setFormOpen(true);
+  }
+
+  function afterSave() {
+    setFormOpen(false);
+    setEditing(null);
+    queryClient.invalidateQueries({ queryKey: queryKeys.biomarkers() });
+    queryClient.invalidateQueries({ queryKey: queryKeys.labResults() });
+  }
+
+  const markers = data?.biomarkers ?? [];
+
+  return (
+    <div className="space-y-4">
+      <div className="flex items-center justify-between gap-3">
+        <p className="text-muted-foreground text-sm">
+          {t("labs.biomarker.managerDescription")}
+        </p>
+        <Button size="sm" onClick={openNew} className="shrink-0">
+          <Plus className="h-4 w-4" />
+          {t("labs.biomarker.define")}
+        </Button>
+      </div>
+
+      {isLoading ? (
+        <div className="space-y-2">
+          {Array.from({ length: 3 }, (_, i) => (
+            <Skeleton key={i} className="h-14 w-full" />
+          ))}
+        </div>
+      ) : isError ? (
+        <p className="text-destructive py-6 text-center text-sm">
+          {t("labs.biomarker.loadError")}
+        </p>
+      ) : markers.length === 0 ? (
+        <EmptyState
+          icon={<FlaskConical className="size-6" />}
+          title={t("labs.biomarker.emptyTitle")}
+          description={t("labs.biomarker.emptyDescription")}
+          action={
+            <Button onClick={openNew}>{t("labs.biomarker.defineFirst")}</Button>
+          }
+        />
+      ) : (
+        <ul className="space-y-2">
+          {markers.map((marker) => {
+            const range = formatReferenceRange(
+              marker.lowerBound,
+              marker.upperBound,
+              formatLabValue,
+            );
+            return (
+              <li key={marker.id}>
+                <Card>
+                  <CardContent className="flex items-center justify-between gap-3 py-3">
+                    <div className="min-w-0">
+                      <div className="flex flex-wrap items-baseline gap-x-2">
+                        <span className="truncate text-sm font-medium">
+                          {marker.name}
+                        </span>
+                        <span className="text-muted-foreground text-xs">
+                          {marker.unit}
+                        </span>
+                      </div>
+                      <p className="text-muted-foreground text-xs">
+                        {range
+                          ? `${t("labs.referenceLabel")} ${range} ${marker.unit}`
+                          : t("labs.biomarker.noRange")}
+                        {marker.panel ? ` · ${marker.panel}` : ""}
+                      </p>
+                    </div>
+                    <div className="flex items-center gap-1">
+                      <Button
+                        size="icon"
+                        variant="ghost"
+                        className="size-9"
+                        onClick={() => openEdit(marker)}
+                        aria-label={t("labs.biomarker.edit")}
+                      >
+                        <Pencil className="h-4 w-4" />
+                      </Button>
+                      <DeleteButton
+                        onConfirm={() => deleteMutation.mutate(marker.id)}
+                        title={t("labs.biomarker.deleteConfirmTitle")}
+                        description={t(
+                          "labs.biomarker.deleteConfirmDescription",
+                        )}
+                        confirmLabel={t("labs.biomarker.delete")}
+                        className="size-9"
+                        iconClassName="h-4 w-4"
+                      />
+                    </div>
+                  </CardContent>
+                </Card>
+              </li>
+            );
+          })}
+        </ul>
+      )}
+
+      <ResponsiveSheet
+        open={formOpen}
+        onOpenChange={setFormOpen}
+        title={
+          editing
+            ? t("labs.biomarker.editTitle")
+            : t("labs.biomarker.defineTitle")
+        }
+        description={t("labs.biomarker.defineDescription")}
+      >
+        <BiomarkerForm
+          existing={editing ?? undefined}
+          onSuccess={afterSave}
+          onCancel={() => setFormOpen(false)}
+        />
+      </ResponsiveSheet>
+    </div>
+  );
+}
@@ -0,0 +1,224 @@
+"use client";
+
+import { useMemo, useState } from "react";
+import {
+  CartesianGrid,
+  ComposedChart,
+  Line,
+  ReferenceArea,
+  ReferenceLine,
+  ResponsiveContainer,
+  Tooltip,
+  XAxis,
+  YAxis,
+} from "recharts";
+
+import { Button } from "@/components/ui/button";
+import { CHART_HEIGHT_PX } from "@/lib/charts/constants";
+import { prefersReducedMotion } from "@/lib/charts/reduced-motion";
+import { formatDateShort } from "@/lib/format";
+import { formatLabValue } from "@/lib/labs/format-value";
+import { useTranslations } from "@/lib/i18n/context";
+
+import { RichChartTooltip, type RichTooltipRow } from "../charts/chart-tooltip";
+import type { LabResultDto } from "./types";
+
+/**
+ * v1.18.1 — per-biomarker trend chart, in the dashboard's visual language.
+ *
+ * Replaces the hand-rolled 72×20 SVG sparkline with a proper Recharts
+ * `ComposedChart`: a single line over time, the catalog reference window
+ * painted as a shaded `ReferenceArea` band with dashed bound lines, range
+ * tabs (30 / 90 / 365 / all), and the shared rich tooltip. The band uses a
+ * MUTED primary fill — never a danger colour — honouring the no-alarming-
+ * colour rule. Every reading carries the same y-axis unit because a chart is
+ * one biomarker only.
+ */
+
+const RANGE_DAYS = [
+  { key: "30", days: 30 },
+  { key: "90", days: 90 },
+  { key: "365", days: 365 },
+  { key: "all", days: 0 },
+] as const;
+
+type RangeKey = (typeof RANGE_DAYS)[number]["key"];
+
+interface ChartPoint {
+  timestamp: number;
+  value: number;
+}
+
+export function LabBiomarkerChart({
+  readings,
+  unit,
+  lowerBound,
+  upperBound,
+}: {
+  /** Readings for this biomarker, any order (sorted internally). */
+  readings: LabResultDto[];
+  unit: string;
+  lowerBound: number | null;
+  upperBound: number | null;
+}) {
+  const { t } = useTranslations();
+  const [range, setRange] = useState<RangeKey>("365");
+  // Capture "now" once at mount so the recency filter stays pure across
+  // re-renders (an inline `Date.now()` in render is impure).
+  const [nowMs] = useState(() => Date.now());
+
+  const points = useMemo<ChartPoint[]>(() => {
+    const sorted = [...readings].sort(
+      (a, b) =>
+        new Date(a.takenAt).getTime() - new Date(b.takenAt).getTime(),
+    );
+    const days = RANGE_DAYS.find((r) => r.key === range)?.days ?? 0;
+    const filtered =
+      days > 0
+        ? sorted.filter((r) => {
+            const ageMs = nowMs - new Date(r.takenAt).getTime();
+            return ageMs <= days * 24 * 60 * 60 * 1000;
+          })
+        : sorted;
+    return filtered.map((r) => ({
+      timestamp: new Date(r.takenAt).getTime(),
+      value: r.value,
+    }));
+  }, [readings, range, nowMs]);
+
+  // Y domain wraps both the data and the reference window so the band is
+  // always visible even when every reading sits inside it.
+  const yDomain = useMemo<[number, number]>(() => {
+    const values = points.map((p) => p.value);
+    const candidates = [...values];
+    if (lowerBound != null) candidates.push(lowerBound);
+    if (upperBound != null) candidates.push(upperBound);
+    if (candidates.length === 0) return [0, 1];
+    const min = Math.min(...candidates);
+    const max = Math.max(...candidates);
+    const pad = (max - min || Math.abs(max) || 1) * 0.1;
+    return [min - pad, max + pad];
+  }, [points, lowerBound, upperBound]);
+
+  const animate = !prefersReducedMotion();
+  const primary = "var(--primary)";
+
+  return (
+    <div className="space-y-3">
+      <div className="flex justify-end gap-1">
+        {RANGE_DAYS.map((r) => (
+          <Button
+            key={r.key}
+            size="sm"
+            variant={range === r.key ? "secondary" : "ghost"}
+            className="h-7 px-2 text-xs"
+            onClick={() => setRange(r.key)}
+          >
+            {t(`labs.chart.range.${r.key}`)}
+          </Button>
+        ))}
+      </div>
+
+      {points.length === 0 ? (
+        <p className="text-muted-foreground py-10 text-center text-sm">
+          {t("labs.chart.empty")}
+        </p>
+      ) : (
+        <div style={{ height: CHART_HEIGHT_PX }}>
+          <ResponsiveContainer width="100%" height="100%">
+            <ComposedChart
+              data={points}
+              margin={{ top: 8, right: 12, bottom: 4, left: 0 }}
+            >
+              <CartesianGrid
+                strokeDasharray="3 3"
+                stroke="var(--border)"
+                vertical={false}
+              />
+              <XAxis
+                dataKey="timestamp"
+                type="number"
+                scale="time"
+                domain={["dataMin", "dataMax"]}
+                tickFormatter={(ts: number) => formatDateShort(new Date(ts))}
+                tick={{ fontSize: 11, fill: "var(--muted-foreground)" }}
+                stroke="var(--border)"
+                minTickGap={32}
+              />
+              <YAxis
+                domain={yDomain}
+                tick={{ fontSize: 11, fill: "var(--muted-foreground)" }}
+                stroke="var(--border)"
+                width={44}
+                tickFormatter={(v: number) => formatLabValue(v)}
+              />
+              {/* Reference window — muted band + dashed bounds. No alarm
+                  colour: the in/out verdict is shown by the neutral badge,
+                  not by painting the chart red. */}
+              {lowerBound != null && upperBound != null ? (
+                <ReferenceArea
+                  y1={lowerBound}
+                  y2={upperBound}
+                  fill={primary}
+                  fillOpacity={0.1}
+                  stroke="none"
+                />
+              ) : null}
+              {lowerBound != null ? (
+                <ReferenceLine
+                  y={lowerBound}
+                  stroke={primary}
+                  strokeOpacity={0.4}
+                  strokeDasharray="4 4"
+                />
+              ) : null}
+              {upperBound != null ? (
+                <ReferenceLine
+                  y={upperBound}
+                  stroke={primary}
+                  strokeOpacity={0.4}
+                  strokeDasharray="4 4"
+                />
+              ) : null}
+              <Tooltip
+                content={(props) => {
+                  const active = props.active ?? false;
+                  const payload = props.payload as
+                    | ReadonlyArray<{ payload?: ChartPoint }>
+                    | undefined;
+                  const point = payload?.[0]?.payload;
+                  if (!active || !point) {
+                    return <RichChartTooltip active={false} rows={[]} />;
+                  }
+                  const rows: RichTooltipRow[] = [
+                    {
+                      name: t("labs.chart.valueLabel"),
+                      value: `${formatLabValue(point.value)} ${unit}`,
+                      color: primary,
+                    },
+                  ];
+                  return (
+                    <RichChartTooltip
+                      active
+                      label={formatDateShort(new Date(point.timestamp))}
+                      rows={rows}
+                    />
+                  );
+                }}
+              />
+              <Line
+                type="monotone"
+                dataKey="value"
+                stroke={primary}
+                strokeWidth={2}
+                dot={{ r: 3, fill: primary }}
+                activeDot={{ r: 5 }}
+                isAnimationActive={animate}
+              />
+            </ComposedChart>
+          </ResponsiveContainer>
+        </div>
+      )}
+    </div>
+  );
+}
@@ -0,0 +1,181 @@
+"use client";
+
+import { useState } from "react";
+import { useQuery, useQueryClient } from "@tanstack/react-query";
+import { FlaskConical, Plus } from "lucide-react";
+
+import { Button } from "@/components/ui/button";
+import { Card, CardContent } from "@/components/ui/card";
+import { EmptyState } from "@/components/ui/empty-state";
+import { ResponsiveSheet } from "@/components/ui/responsive-sheet";
+import { Skeleton } from "@/components/ui/skeleton";
+import { apiGet } from "@/lib/api/api-fetch";
+import { classifyReferenceRange } from "@/lib/labs/reference-range";
+import { formatLabValue } from "@/lib/labs/format-value";
+import { useTranslations } from "@/lib/i18n/context";
+import { queryKeys } from "@/lib/query-keys";
+
+import { LabBiomarkerChart } from "./lab-biomarker-chart";
+import { LabForm } from "./lab-form";
+import { LabHistoryList } from "./lab-history-list";
+import { ReferenceRangeBadge } from "./reference-range-badge";
+import type {
+  BiomarkerDto,
+  LabResultDto,
+  LabResultListResponse,
+} from "./types";
+
+/**
+ * v1.18.1 — per-biomarker detail: heading + current-value badge, the proper
+ * dashboard-style chart with the reference band, and the editable reading
+ * history. "Add value" pre-selects this biomarker so the user never re-picks
+ * it. Mirrors the measurement-detail layout.
+ */
+export function LabBiomarkerDetail({ biomarkerId }: { biomarkerId: string }) {
+  const { t } = useTranslations();
+  const queryClient = useQueryClient();
+  const [addOpen, setAddOpen] = useState(false);
+
+  const { data: marker, isError: markerError } = useQuery({
+    queryKey: queryKeys.biomarkerDetail(biomarkerId),
+    queryFn: () => apiGet<BiomarkerDto>(`/api/biomarkers/${biomarkerId}`),
+  });
+
+  const {
+    data: list,
+    isLoading,
+    isError: listError,
+  } = useQuery({
+    queryKey: queryKeys.labResultsList({
+      biomarkerId,
+      analyte: undefined,
+      panel: undefined,
+      from: undefined,
+      to: undefined,
+      page: 0,
+      sortDir: "desc",
+    }),
+    queryFn: () =>
+      apiGet<LabResultListResponse>(
+        `/api/labs?biomarkerId=${encodeURIComponent(biomarkerId)}&limit=500&sortDir=desc`,
+      ),
+  });
+
+  const readings: LabResultDto[] = list?.results ?? [];
+  const latest =
+    readings.length > 0
+      ? [...readings].sort(
+          (a, b) =>
+            new Date(b.takenAt).getTime() - new Date(a.takenAt).getTime(),
+        )[0]
+      : null;
+
+  function afterAdd() {
+    setAddOpen(false);
+    queryClient.invalidateQueries({ queryKey: queryKeys.labResults() });
+  }
+
+  if (markerError || listError) {
+    return (
+      <p className="text-destructive py-8 text-center text-sm">
+        {t("labs.loadError")}
+      </p>
+    );
+  }
+
+  const latestStatus = latest
+    ? classifyReferenceRange(
+        latest.value,
+        marker?.lowerBound ?? null,
+        marker?.upperBound ?? null,
+      )
+    : "unknown";
+
+  return (
+    <div className="space-y-6">
+      <div className="flex items-start justify-between gap-3">
+        <div className="min-w-0">
+          <h1 className="text-2xl font-bold tracking-tight">
+            {marker?.name ?? <Skeleton className="h-7 w-32" />}
+          </h1>
+          {marker?.unit ? (
+            <p className="text-muted-foreground text-xs sm:text-sm">
+              {marker.unit}
+              {marker.panel ? ` · ${marker.panel}` : ""}
+            </p>
+          ) : null}
+        </div>
+        <Button onClick={() => setAddOpen(true)} className="shrink-0">
+          <Plus className="h-4 w-4" />
+          {t("labs.addResult")}
+        </Button>
+      </div>
+
+      {latest ? (
+        <div className="flex flex-wrap items-baseline gap-x-3 gap-y-1">
+          <span className="text-2xl font-bold tabular-nums">
+            {formatLabValue(latest.value)}{" "}
+            <span className="text-muted-foreground text-base font-normal">
+              {marker?.unit ?? latest.unit}
+            </span>
+          </span>
+          <ReferenceRangeBadge status={latestStatus} />
+        </div>
+      ) : null}
+
+      {marker?.context ? (
+        <p className="text-muted-foreground text-sm">{marker.context}</p>
+      ) : null}
+
+      <Card>
+        <CardContent className="pt-6">
+          {isLoading ? (
+            <Skeleton className="h-60 w-full" />
+          ) : readings.length === 0 ? (
+            <EmptyState
+              icon={<FlaskConical className="size-6" />}
+              title={t("labs.detail.emptyTitle")}
+              description={t("labs.detail.emptyDescription")}
+              action={
+                <Button onClick={() => setAddOpen(true)}>
+                  {t("labs.addResult")}
+                </Button>
+              }
+            />
+          ) : (
+            <LabBiomarkerChart
+              readings={readings}
+              unit={marker?.unit ?? latest?.unit ?? ""}
+              lowerBound={marker?.lowerBound ?? null}
+              upperBound={marker?.upperBound ?? null}
+            />
+          )}
+        </CardContent>
+      </Card>
+
+      {readings.length > 0 ? (
+        <div className="space-y-2">
+          <h2 className="text-sm font-semibold">{t("labs.detail.history")}</h2>
+          <Card>
+            <CardContent className="py-0">
+              <LabHistoryList readings={readings} />
+            </CardContent>
+          </Card>
+        </div>
+      ) : null}
+
+      <ResponsiveSheet
+        open={addOpen}
+        onOpenChange={setAddOpen}
+        title={t("labs.addResult")}
+        description={t("labs.addDescription")}
+      >
+        <LabForm
+          lockedBiomarkerId={biomarkerId}
+          onSuccess={afterAdd}
+          onCancel={() => setAddOpen(false)}
+        />
+      </ResponsiveSheet>
+    </div>
+  );
+}
@@ -1,6 +1,7 @@
 "use client";

 import { useState } from "react";
+import { useQuery, useQueryClient } from "@tanstack/react-query";
 import { Loader2 } from "lucide-react";
 import { toast } from "sonner";

@@ -8,13 +9,30 @@ import { Button } from "@/components/ui/button";
 import { DateTimeInput } from "@/components/ui/date-input";
 import { Input } from "@/components/ui/input";
 import { Label } from "@/components/ui/label";
+import { ResponsiveSheet } from "@/components/ui/responsive-sheet";
+import {
+  Select,
+  SelectContent,
+  SelectItem,
+  SelectTrigger,
+  SelectValue,
+} from "@/components/ui/select";
 import { Textarea } from "@/components/ui/textarea";
-import { ApiError, apiPost } from "@/lib/api/api-fetch";
+import { ApiError, apiGet, apiPost } from "@/lib/api/api-fetch";
+import { formatReferenceRange } from "@/lib/labs/reference-range";
+import { formatLabValue } from "@/lib/labs/format-value";
 import { useTranslations } from "@/lib/i18n/context";
+import { queryKeys } from "@/lib/query-keys";

-import type { LabResultDto } from "./types";
+import { BiomarkerForm } from "./biomarker-form";
+import type {
+  BiomarkerDto,
+  BiomarkerListResponse,
+  LabResultDto,
+} from "./types";

 const NOTE_MAX_LENGTH = 2000;
+const DEFINE_NEW = "__define_new__";

 function defaultTakenAtValue() {
  const now = new Date();
@@ -32,59 +50,83 @@ function parseDecimal(raw: string): number | null {
 }

 interface LabFormProps {
+  /** When set, the biomarker is pre-selected and locked (add-from-detail). */
+  lockedBiomarkerId?: string;
  onSuccess?: (created: LabResultDto) => void;
  onCancel?: () => void;
 }

 /**
- * v1.17.1 — manual lab-result entry.
+ * v1.18.1 — structured lab-result entry.
 *
- * Progressive disclosure: the four essentials (analyte, value, unit, date)
- * are always visible; the optional reference range, panel grouping, and
- * note sit below under a clearly-labelled "optional" heading so a quick
- * single-value entry stays a four-field affair.
+ * The error-prone free-text path is gone: the user PICKS a biomarker from the
+ * catalog, then enters only the value against its known unit + reference range
+ * (resolved server-side). A "+ define new" row opens the marker-definition
+ * sheet inline and returns with it selected. Panel / unit / range are NOT
+ * re-entered per reading — they live on the biomarker. Only the per-reading
+ * note stays optional here.
 */
-export function LabForm({ onSuccess, onCancel }: LabFormProps) {
+export function LabForm({
+  lockedBiomarkerId,
+  onSuccess,
+  onCancel,
+}: LabFormProps) {
  const { t } = useTranslations();
+  const queryClient = useQueryClient();

-  const [analyte, setAnalyte] = useState("");
+  const { data: catalog, isLoading: catalogLoading } = useQuery({
+    queryKey: queryKeys.biomarkers(),
+    queryFn: () => apiGet<BiomarkerListResponse>("/api/biomarkers"),
+  });
+
+  const [biomarkerId, setBiomarkerId] = useState<string>(
+    lockedBiomarkerId ?? "",
+  );
  const [value, setValue] = useState("");
-  const [unit, setUnit] = useState("");
  const [takenAt, setTakenAt] = useState(defaultTakenAtValue);
-  const [panel, setPanel] = useState("");
-  const [refLow, setRefLow] = useState("");
-  const [refHigh, setRefHigh] = useState("");
  const [note, setNote] = useState("");
  const [submitting, setSubmitting] = useState(false);
  const [error, setError] = useState<string | null>(null);
+  const [defineOpen, setDefineOpen] = useState(false);
+
+  const markers = catalog?.biomarkers ?? [];
+  const selected = markers.find((m) => m.id === biomarkerId);
+
+  function handleSelect(next: string) {
+    if (next === DEFINE_NEW) {
+      setDefineOpen(true);
+      return;
+    }
+    setBiomarkerId(next);
+    setError(null);
+  }
+
+  function afterDefine(created: BiomarkerDto) {
+    setDefineOpen(false);
+    queryClient.invalidateQueries({ queryKey: queryKeys.biomarkers() });
+    setBiomarkerId(created.id);
+  }

  async function handleSubmit(e: React.FormEvent) {
    e.preventDefault();
    setError(null);

    const numericValue = parseDecimal(value);
-    if (!analyte.trim() || numericValue === null || !unit.trim()) {
-      setError(t("labs.form.requiredError"));
+    if (!biomarkerId) {
+      setError(t("labs.form.pickBiomarkerError"));
      return;
    }
-
-    const low = parseDecimal(refLow);
-    const high = parseDecimal(refHigh);
-    if (low !== null && high !== null && low > high) {
-      setError(t("labs.form.rangeOrderError"));
+    if (numericValue === null) {
+      setError(t("labs.form.requiredError"));
      return;
    }

    setSubmitting(true);
    try {
      const created = await apiPost<LabResultDto>("/api/labs", {
-        analyte: analyte.trim(),
+        biomarkerId,
        value: numericValue,
-        unit: unit.trim(),
        takenAt: new Date(takenAt).toISOString(),
-        ...(panel.trim() ? { panel: panel.trim() } : {}),
-        ...(low !== null ? { referenceLow: low } : {}),
-        ...(high !== null ? { referenceHigh: high } : {}),
        ...(note.trim() ? { note: note.trim() } : {}),
      });
      toast.success(t("labs.form.savedToast"));
@@ -98,94 +140,87 @@ export function LabForm({ onSuccess, onCancel }: LabFormProps) {
    }
  }

-  return (
-    <form onSubmit={handleSubmit} className="space-y-5">
-      <div className="grid gap-4 sm:grid-cols-2">
-        <div className="space-y-1.5 sm:col-span-2">
-          <Label htmlFor="lab-analyte">{t("labs.form.analyte")}</Label>
-          <Input
-            id="lab-analyte"
-            value={analyte}
-            onChange={(e) => setAnalyte(e.target.value)}
-            placeholder={t("labs.form.analytePlaceholder")}
-            maxLength={120}
-            autoFocus
-            required
-          />
-        </div>
-        <div className="space-y-1.5">
-          <Label htmlFor="lab-value">{t("labs.form.value")}</Label>
-          <Input
-            id="lab-value"
-            inputMode="decimal"
-            value={value}
-            onChange={(e) => setValue(e.target.value)}
-            placeholder="0.0"
-            required
-          />
-        </div>
-        <div className="space-y-1.5">
-          <Label htmlFor="lab-unit">{t("labs.form.unit")}</Label>
-          <Input
-            id="lab-unit"
-            value={unit}
-            onChange={(e) => setUnit(e.target.value)}
-            placeholder={t("labs.form.unitPlaceholder")}
-            maxLength={40}
-            required
-          />
-        </div>
-        <div className="space-y-1.5 sm:col-span-2">
-          <Label htmlFor="lab-takenAt">{t("labs.form.takenAt")}</Label>
-          <DateTimeInput
-            id="lab-takenAt"
-            value={takenAt}
-            onChange={(e) => setTakenAt(e.target.value)}
-            max={defaultTakenAtValue()}
-            required
-          />
-        </div>
-      </div>
+  const referenceText = selected
+    ? formatReferenceRange(
+        selected.lowerBound,
+        selected.upperBound,
+        formatLabValue,
+      )
+    : "";

-      <fieldset className="space-y-4 rounded-lg border border-dashed p-4">
-        <legend className="text-muted-foreground px-1 text-xs font-medium">
-          {t("labs.form.optionalGroup")}
-        </legend>
+  return (
+    <>
+      <form onSubmit={handleSubmit} className="space-y-5">
        <div className="space-y-1.5">
-          <Label htmlFor="lab-panel">{t("labs.form.panel")}</Label>
-          <Input
-            id="lab-panel"
-            value={panel}
-            onChange={(e) => setPanel(e.target.value)}
-            placeholder={t("labs.form.panelPlaceholder")}
-            maxLength={120}
-          />
+          <Label htmlFor="lab-biomarker">{t("labs.form.biomarker")}</Label>
+          <Select
+            value={biomarkerId || undefined}
+            onValueChange={handleSelect}
+            disabled={!!lockedBiomarkerId || catalogLoading}
+          >
+            <SelectTrigger id="lab-biomarker" className="w-full">
+              <SelectValue
+                placeholder={t("labs.form.biomarkerPlaceholder")}
+              />
+            </SelectTrigger>
+            <SelectContent>
+              {markers.map((m) => (
+                <SelectItem key={m.id} value={m.id}>
+                  {m.name} · {m.unit}
+                </SelectItem>
+              ))}
+              {!lockedBiomarkerId ? (
+                <SelectItem value={DEFINE_NEW}>
+                  {t("labs.form.defineNew")}
+                </SelectItem>
+              ) : null}
+            </SelectContent>
+          </Select>
+          {markers.length === 0 && !catalogLoading ? (
+            <p className="text-muted-foreground text-xs">
+              {t("labs.form.noBiomarkersHint")}
+            </p>
+          ) : null}
        </div>
+
        <div className="grid gap-4 sm:grid-cols-2">
          <div className="space-y-1.5">
-            <Label htmlFor="lab-refLow">{t("labs.form.referenceLow")}</Label>
+            <Label htmlFor="lab-value">
+              {t("labs.form.value")}
+              {selected ? (
+                <span className="text-muted-foreground font-normal">
+                  {" "}
+                  ({selected.unit})
+                </span>
+              ) : null}
+            </Label>
            <Input
-              id="lab-refLow"
+              id="lab-value"
              inputMode="decimal"
-              value={refLow}
-              onChange={(e) => setRefLow(e.target.value)}
-              placeholder={t("labs.form.referenceLowPlaceholder")}
+              value={value}
+              onChange={(e) => setValue(e.target.value)}
+              placeholder="0.0"
+              required
            />
          </div>
          <div className="space-y-1.5">
-            <Label htmlFor="lab-refHigh">{t("labs.form.referenceHigh")}</Label>
-            <Input
-              id="lab-refHigh"
-              inputMode="decimal"
-              value={refHigh}
-              onChange={(e) => setRefHigh(e.target.value)}
-              placeholder={t("labs.form.referenceHighPlaceholder")}
+            <Label htmlFor="lab-takenAt">{t("labs.form.takenAt")}</Label>
+            <DateTimeInput
+              id="lab-takenAt"
+              value={takenAt}
+              onChange={(e) => setTakenAt(e.target.value)}
+              max={defaultTakenAtValue()}
+              required
            />
          </div>
        </div>
-        <p className="text-muted-foreground text-xs">
-          {t("labs.form.referenceHint")}
-        </p>
+
+        {selected && referenceText ? (
+          <p className="text-muted-foreground text-xs">
+            {t("labs.referenceLabel")} {referenceText} {selected.unit}
+          </p>
+        ) : null}
+
        <div className="space-y-1.5">
          <Label htmlFor="lab-note">{t("labs.form.note")}</Label>
          <Textarea
@@ -197,32 +232,44 @@ export function LabForm({ onSuccess, onCancel }: LabFormProps) {
            rows={2}
          />
        </div>
-      </fieldset>

-      {error ? (
-        <p className="text-destructive text-sm" role="alert">
-          {error}
-        </p>
-      ) : null}
-
-      <div className="flex justify-end gap-2">
-        {onCancel ? (
-          <Button
-            type="button"
-            variant="ghost"
-            onClick={onCancel}
-            disabled={submitting}
-          >
-            {t("common.cancel")}
-          </Button>
+        {error ? (
+          <p className="text-destructive text-sm" role="alert">
+            {error}
+          </p>
        ) : null}
-        <Button type="submit" disabled={submitting}>
-          {submitting ? (
-            <Loader2 className="h-4 w-4 animate-spin motion-reduce:animate-none" />
+
+        <div className="flex justify-end gap-2">
+          {onCancel ? (
+            <Button
+              type="button"
+              variant="ghost"
+              onClick={onCancel}
+              disabled={submitting}
+            >
+              {t("common.cancel")}
+            </Button>
          ) : null}
-          {t("labs.form.save")}
-        </Button>
-      </div>
-    </form>
+          <Button type="submit" disabled={submitting}>
+            {submitting ? (
+              <Loader2 className="h-4 w-4 animate-spin motion-reduce:animate-none" />
+            ) : null}
+            {t("labs.form.save")}
+          </Button>
+        </div>
+      </form>
+
+      <ResponsiveSheet
+        open={defineOpen}
+        onOpenChange={setDefineOpen}
+        title={t("labs.biomarker.defineTitle")}
+        description={t("labs.biomarker.defineDescription")}
+      >
+        <BiomarkerForm
+          onSuccess={afterDefine}
+          onCancel={() => setDefineOpen(false)}
+        />
+      </ResponsiveSheet>
+    </>
  );
 }
@@ -0,0 +1,271 @@
+"use client";
+
+import { useState } from "react";
+import { useMutation, useQueryClient } from "@tanstack/react-query";
+import { Loader2, Pencil } from "lucide-react";
+import { toast } from "sonner";
+
+import { DeleteButton } from "@/components/data-list";
+import { Button } from "@/components/ui/button";
+import { DateTimeInput } from "@/components/ui/date-input";
+import { Input } from "@/components/ui/input";
+import { Label } from "@/components/ui/label";
+import { ResponsiveSheet } from "@/components/ui/responsive-sheet";
+import { Textarea } from "@/components/ui/textarea";
+import { ApiError, apiDelete, apiGet, apiPost, apiPut } from "@/lib/api/api-fetch";
+import { formatDateShort } from "@/lib/format";
+import { formatLabValue } from "@/lib/labs/format-value";
+import { useTranslations } from "@/lib/i18n/context";
+import { queryKeys } from "@/lib/query-keys";
+
+import { ReferenceRangeBadge } from "./reference-range-badge";
+import type { LabResultDetailDto, LabResultDto } from "./types";
+
+const NOTE_MAX_LENGTH = 2000;
+
+function toDateTimeLocal(iso: string): string {
+  const d = new Date(iso);
+  const offset = d.getTimezoneOffset();
+  const local = new Date(d.getTime() - offset * 60 * 1000);
+  return local.toISOString().slice(0, 16);
+}
+
+function parseDecimal(raw: string): number | null {
+  const trimmed = raw.trim().replace(",", ".");
+  if (trimmed === "") return null;
+  const n = Number(trimmed);
+  return Number.isFinite(n) ? n : null;
+}
+
+/**
+ * v1.18.1 — reverse-chronological reading history for one biomarker, with
+ * full edit / amend / delete (L5). Edit opens a sheet that loads the
+ * decrypted note from the single-resource GET; delete soft-deletes with an
+ * Undo toast that restores via `/api/labs/restore` (the measurement pattern).
+ */
+export function LabHistoryList({ readings }: { readings: LabResultDto[] }) {
+  const { t } = useTranslations();
+  const queryClient = useQueryClient();
+
+  const [editingId, setEditingId] = useState<string | null>(null);
+  const [editValue, setEditValue] = useState("");
+  const [editTakenAt, setEditTakenAt] = useState("");
+  const [editNote, setEditNote] = useState("");
+  const [editLoading, setEditLoading] = useState(false);
+  const [editError, setEditError] = useState<string | null>(null);
+
+  function invalidate() {
+    queryClient.invalidateQueries({ queryKey: queryKeys.labResults() });
+  }
+
+  async function restore(id: string) {
+    try {
+      await apiPost("/api/labs/restore", { ids: [id] });
+      invalidate();
+      toast.success(t("labs.restoredToast"));
+    } catch {
+      toast.error(t("labs.restoreError"));
+    }
+  }
+
+  const deleteMutation = useMutation({
+    mutationFn: (id: string) => apiDelete(`/api/labs/${id}`),
+    onSuccess: (_data, id) => {
+      invalidate();
+      toast.success(t("labs.deletedToast"), {
+        action: {
+          label: t("common.undo"),
+          onClick: () => void restore(id),
+        },
+      });
+    },
+    onError: () => toast.error(t("labs.deleteError")),
+  });
+
+  const updateMutation = useMutation({
+    mutationFn: (body: {
+      id: string;
+      value: number;
+      takenAt: string;
+      note: string | null;
+    }) =>
+      apiPut<LabResultDto>(`/api/labs/${body.id}`, {
+        value: body.value,
+        takenAt: body.takenAt,
+        note: body.note,
+      }),
+    onSuccess: () => {
+      invalidate();
+      toast.success(t("labs.editedToast"));
+      closeEdit();
+    },
+    onError: (err) => {
+      setEditError(
+        err instanceof ApiError ? err.message : t("labs.editError"),
+      );
+    },
+  });
+
+  async function openEdit(reading: LabResultDto) {
+    setEditingId(reading.id);
+    setEditValue(String(reading.value));
+    setEditTakenAt(toDateTimeLocal(reading.takenAt));
+    setEditNote("");
+    setEditError(null);
+    // Load the decrypted note (list rows withhold it).
+    setEditLoading(true);
+    try {
+      const detail = await apiGet<LabResultDetailDto>(
+        `/api/labs/${reading.id}`,
+      );
+      setEditNote(detail.note ?? "");
+    } catch {
+      /* leave note blank on a load miss */
+    } finally {
+      setEditLoading(false);
+    }
+  }
+
+  function closeEdit() {
+    if (updateMutation.isPending) return;
+    setEditingId(null);
+    setEditError(null);
+  }
+
+  function submitEdit(e: React.FormEvent) {
+    e.preventDefault();
+    if (!editingId) return;
+    const numericValue = parseDecimal(editValue);
+    if (numericValue === null) {
+      setEditError(t("labs.form.requiredError"));
+      return;
+    }
+    const takenDate = new Date(editTakenAt);
+    if (Number.isNaN(takenDate.getTime())) {
+      setEditError(t("labs.editTimestampError"));
+      return;
+    }
+    updateMutation.mutate({
+      id: editingId,
+      value: numericValue,
+      takenAt: takenDate.toISOString(),
+      note: editNote.trim() ? editNote.trim() : null,
+    });
+  }
+
+  const ordered = [...readings].sort(
+    (a, b) => new Date(b.takenAt).getTime() - new Date(a.takenAt).getTime(),
+  );
+
+  return (
+    <>
+      <ul className="divide-border divide-y">
+        {ordered.map((r) => (
+          <li
+            key={r.id}
+            className="flex items-center justify-between gap-3 py-3"
+          >
+            <div className="min-w-0">
+              <div className="flex flex-wrap items-baseline gap-x-2">
+                <span className="text-foreground font-semibold tabular-nums">
+                  {formatLabValue(r.value)} {r.unit}
+                </span>
+                <ReferenceRangeBadge status={r.rangeStatus} />
+              </div>
+              <p className="text-muted-foreground text-xs">
+                {formatDateShort(r.takenAt, true)}
+                {r.hasNote ? ` · ${t("labs.hasNote")}` : ""}
+              </p>
+            </div>
+            <div className="flex items-center gap-1">
+              <Button
+                size="icon"
+                variant="ghost"
+                className="size-9"
+                onClick={() => void openEdit(r)}
+                aria-label={t("labs.editReading")}
+              >
+                <Pencil className="h-4 w-4" />
+              </Button>
+              <DeleteButton
+                onConfirm={() => deleteMutation.mutate(r.id)}
+                title={t("labs.deleteConfirmTitle")}
+                description={t("labs.deleteConfirmDescription")}
+                confirmLabel={t("labs.deleteReading")}
+                className="size-9"
+                iconClassName="h-4 w-4"
+              />
+            </div>
+          </li>
+        ))}
+      </ul>
+
+      <ResponsiveSheet
+        open={editingId !== null}
+        onOpenChange={(open) => {
+          if (!open) closeEdit();
+        }}
+        title={t("labs.editTitle")}
+        description={t("labs.editDescription")}
+      >
+        <form onSubmit={submitEdit} className="space-y-5">
+          <div className="grid gap-4 sm:grid-cols-2">
+            <div className="space-y-1.5">
+              <Label htmlFor="lab-edit-value">{t("labs.form.value")}</Label>
+              <Input
+                id="lab-edit-value"
+                inputMode="decimal"
+                value={editValue}
+                onChange={(e) => setEditValue(e.target.value)}
+                required
+              />
+            </div>
+            <div className="space-y-1.5">
+              <Label htmlFor="lab-edit-takenAt">
+                {t("labs.form.takenAt")}
+              </Label>
+              <DateTimeInput
+                id="lab-edit-takenAt"
+                value={editTakenAt}
+                onChange={(e) => setEditTakenAt(e.target.value)}
+                required
+              />
+            </div>
+          </div>
+          <div className="space-y-1.5">
+            <Label htmlFor="lab-edit-note">{t("labs.form.note")}</Label>
+            <Textarea
+              id="lab-edit-note"
+              value={editNote}
+              onChange={(e) => setEditNote(e.target.value)}
+              maxLength={NOTE_MAX_LENGTH}
+              rows={2}
+              disabled={editLoading}
+            />
+          </div>
+          {editError ? (
+            <p className="text-destructive text-sm" role="alert">
+              {editError}
+            </p>
+          ) : null}
+          <div className="flex justify-end gap-2">
+            <Button
+              type="button"
+              variant="ghost"
+              onClick={closeEdit}
+              disabled={updateMutation.isPending}
+            >
+              {t("common.cancel")}
+            </Button>
+            <Button type="submit" disabled={updateMutation.isPending}>
+              {updateMutation.isPending ? (
+                <Loader2 className="h-4 w-4 animate-spin motion-reduce:animate-none" />
+              ) : null}
+              {t("common.save")}
+            </Button>
+          </div>
+        </form>
+      </ResponsiveSheet>
+    </>
+  );
+}
@@ -1,24 +1,23 @@
 "use client";

 import { useMemo } from "react";
-import { useMutation, useQuery, useQueryClient } from "@tanstack/react-query";
-import { FlaskConical } from "lucide-react";
-import { toast } from "sonner";
+import Link from "next/link";
+import { useQuery } from "@tanstack/react-query";
+import { ChevronRight, FlaskConical } from "lucide-react";

-import { DeleteButton } from "@/components/data-list";
-import { formatReferenceRange } from "@/lib/labs/reference-range";
 import { Button } from "@/components/ui/button";
 import {
  Card,
-  CardAction,
  CardContent,
  CardHeader,
  CardTitle,
 } from "@/components/ui/card";
 import { EmptyState } from "@/components/ui/empty-state";
 import { Skeleton } from "@/components/ui/skeleton";
-import { apiDelete, apiGet } from "@/lib/api/api-fetch";
+import { apiGet } from "@/lib/api/api-fetch";
 import { formatDate } from "@/lib/format";
+import { formatReferenceRange } from "@/lib/labs/reference-range";
+import { formatLabValue } from "@/lib/labs/format-value";
 import { useTranslations } from "@/lib/i18n/context";
 import { queryKeys } from "@/lib/query-keys";

@@ -26,34 +25,44 @@ import { LabTrendSparkline } from "./lab-trend-sparkline";
 import { ReferenceRangeBadge } from "./reference-range-badge";
 import type { LabResultDto, LabResultListResponse } from "./types";

-interface AnalyteGroup {
+interface MarkerGroup {
+  /** Stable group key: the biomarker id, or `analyte:<lower>` for legacy rows. */
+  key: string;
+  /** Link target when the group is catalog-linked; null for legacy rows. */
+  biomarkerId: string | null;
  analyte: string;
  panel: string | null;
  unit: string;
-  /** All readings for this analyte, oldest → newest. */
  readings: LabResultDto[];
  latest: LabResultDto;
 }

-/** Reduce the flat result list into per-analyte groups (case-insensitive). */
-function groupByAnalyte(results: LabResultDto[]): AnalyteGroup[] {
+/**
+ * Group readings by their linked biomarker (or, for legacy un-linked rows,
+ * case-insensitively by analyte). A catalog-linked group deep-links to its
+ * detail chart; legacy groups render inert until the backfill links them.
+ */
+function groupReadings(results: LabResultDto[]): MarkerGroup[] {
  const byKey = new Map<string, LabResultDto[]>();
  for (const r of results) {
-    const key = r.analyte.toLowerCase();
-    const existing = byKey.get(key);
-    if (existing) existing.push(r);
+    const key = r.biomarkerId
+      ? `bm:${r.biomarkerId}`
+      : `analyte:${r.analyte.toLowerCase()}`;
+    const bucket = byKey.get(key);
+    if (bucket) bucket.push(r);
    else byKey.set(key, [r]);
  }
-  const groups: AnalyteGroup[] = [];
-  for (const readings of byKey.values()) {
-    // Ascending by takenAt so the sparkline reads left→right in time and
-    // the last element is the latest.
+
+  const groups: MarkerGroup[] = [];
+  for (const [key, readings] of byKey.entries()) {
    const ordered = [...readings].sort(
      (a, b) =>
        new Date(a.takenAt).getTime() - new Date(b.takenAt).getTime(),
    );
    const latest = ordered[ordered.length - 1];
    groups.push({
+      key,
+      biomarkerId: latest.biomarkerId,
      analyte: latest.analyte,
      panel: latest.panel,
      unit: latest.unit,
@@ -61,7 +70,6 @@ function groupByAnalyte(results: LabResultDto[]): AnalyteGroup[] {
      latest,
    });
  }
-  // Group order: most-recently-updated analyte first.
  return groups.sort(
    (a, b) =>
      new Date(b.latest.takenAt).getTime() -
@@ -69,16 +77,11 @@ function groupByAnalyte(results: LabResultDto[]): AnalyteGroup[] {
  );
 }

-function formatValue(value: number): string {
-  // Trim trailing zeros for whole numbers; keep up to 2 decimals otherwise.
-  return Number.isInteger(value) ? String(value) : String(Number(value.toFixed(2)));
-}
-
 export function LabList({ onAddFirst }: { onAddFirst?: () => void } = {}) {
  const { t } = useTranslations();
-  const queryClient = useQueryClient();

  const listKey = queryKeys.labResultsList({
+    biomarkerId: undefined,
    analyte: undefined,
    panel: undefined,
    from: undefined,
@@ -89,25 +92,12 @@ export function LabList({ onAddFirst }: { onAddFirst?: () => void } = {}) {

  const { data, isLoading, isError } = useQuery({
    queryKey: listKey,
-    queryFn: async () => {
-      const res = await apiGet<LabResultListResponse>(
-        "/api/labs?limit=500&sortDir=desc",
-      );
-      return res;
-    },
-  });
-
-  const deleteMutation = useMutation({
-    mutationFn: (id: string) => apiDelete(`/api/labs/${id}`),
-    onSuccess: () => {
-      toast.success(t("labs.deletedToast"));
-      queryClient.invalidateQueries({ queryKey: queryKeys.labResults() });
-    },
-    onError: () => toast.error(t("labs.deleteError")),
+    queryFn: () =>
+      apiGet<LabResultListResponse>("/api/labs?limit=500&sortDir=desc"),
  });

  const groups = useMemo(
-    () => groupByAnalyte(data?.results ?? []),
+    () => groupReadings(data?.results ?? []),
    [data?.results],
  );

@@ -154,60 +144,76 @@ export function LabList({ onAddFirst }: { onAddFirst?: () => void } = {}) {

  return (
    <div className="space-y-3">
-      {groups.map((group) => (
-        <Card key={group.analyte.toLowerCase()}>
-          <CardHeader>
-            <CardTitle className="flex flex-wrap items-baseline gap-x-2 gap-y-1 text-sm">
-              <span className="font-medium">{group.analyte}</span>
-              {group.panel ? (
-                <span className="text-muted-foreground text-xs font-normal">
-                  {group.panel}
-                </span>
-              ) : null}
-              <ReferenceRangeBadge status={group.latest.rangeStatus} />
-            </CardTitle>
-            <CardAction className="flex items-center gap-3">
-              <LabTrendSparkline values={group.readings.map((r) => r.value)} />
-              <DeleteButton
-                onConfirm={() => deleteMutation.mutate(group.latest.id)}
-                title={t("labs.deleteConfirmTitle")}
-                description={t("labs.deleteConfirmDescription")}
-                confirmLabel={t("labs.deleteLatest")}
-                className="size-9"
-                iconClassName="h-4 w-4"
-              />
-            </CardAction>
-          </CardHeader>
-          <CardContent>
-            <div className="text-muted-foreground flex flex-wrap items-center gap-x-2 text-sm">
-              <span className="text-foreground font-semibold tabular-nums">
-                {formatValue(group.latest.value)} {group.latest.unit}
-              </span>
-              {group.latest.referenceLow !== null ||
-              group.latest.referenceHigh !== null ? (
-                <span className="text-xs">
-                  {t("labs.referenceLabel")}{" "}
-                  {formatReferenceRange(
-                    group.latest.referenceLow,
-                    group.latest.referenceHigh,
-                    formatValue,
-                  )}
-                </span>
-              ) : null}
-              <span className="text-xs">
-                {formatDate(group.latest.takenAt)}
-              </span>
-              {group.readings.length > 1 ? (
-                <span className="text-xs">
-                  {t("labs.readingsCount", {
-                    count: group.readings.length,
-                  })}
-                </span>
-              ) : null}
-            </div>
-          </CardContent>
-        </Card>
-      ))}
+      {groups.map((group) => {
+        const body = (
+          <>
+            <CardHeader>
+              <CardTitle className="flex flex-wrap items-baseline gap-x-2 gap-y-1 text-sm">
+                <span className="font-medium">{group.analyte}</span>
+                {group.panel ? (
+                  <span className="text-muted-foreground text-xs font-normal">
+                    {group.panel}
+                  </span>
+                ) : null}
+                <ReferenceRangeBadge status={group.latest.rangeStatus} />
+              </CardTitle>
+            </CardHeader>
+            <CardContent>
+              <div className="flex items-center justify-between gap-3">
+                <div className="text-muted-foreground flex flex-wrap items-center gap-x-2 text-sm">
+                  <span className="text-foreground font-semibold tabular-nums">
+                    {formatLabValue(group.latest.value)} {group.latest.unit}
+                  </span>
+                  {group.latest.referenceLow !== null ||
+                  group.latest.referenceHigh !== null ? (
+                    <span className="text-xs">
+                      {t("labs.referenceLabel")}{" "}
+                      {formatReferenceRange(
+                        group.latest.referenceLow,
+                        group.latest.referenceHigh,
+                        formatLabValue,
+                      )}
+                    </span>
+                  ) : null}
+                  <span className="text-xs">
+                    {formatDate(group.latest.takenAt)}
+                  </span>
+                  {group.readings.length > 1 ? (
+                    <span className="text-xs">
+                      {t("labs.readingsCount", {
+                        count: group.readings.length,
+                      })}
+                    </span>
+                  ) : null}
+                </div>
+                <div className="flex items-center gap-2">
+                  <LabTrendSparkline
+                    values={group.readings.map((r) => r.value)}
+                  />
+                  {group.biomarkerId ? (
+                    <ChevronRight className="text-muted-foreground h-4 w-4 shrink-0" />
+                  ) : null}
+                </div>
+              </div>
+            </CardContent>
+          </>
+        );
+
+        // Catalog-linked groups deep-link to the per-biomarker detail chart.
+        // Legacy un-linked groups render as a plain card until the backfill
+        // links them (or the user re-adds via the structured path).
+        return group.biomarkerId ? (
+          <Link
+            key={group.key}
+            href={`/labs/${group.biomarkerId}`}
+            className="block"
+          >
+            <Card className="hover:bg-muted/40 transition-colors">{body}</Card>
+          </Link>
+        ) : (
+          <Card key={group.key}>{body}</Card>
+        );
+      })}
    </div>
  );
 }
@@ -3,6 +3,8 @@ import type { ReferenceRangeStatus } from "@/lib/validations/labs";
 /** A lab-result row as the list / create endpoints serialise it. */
 export interface LabResultDto {
  id: string;
+  /** v1.18.1 — link to the catalog marker (null for legacy free-text rows). */
+  biomarkerId: string | null;
  panel: string | null;
  analyte: string;
  value: number;
@@ -17,7 +19,30 @@ export interface LabResultDto {
  updatedAt: string;
 }

+/** The single-resource detail DTO — carries the decrypted note. */
+export interface LabResultDetailDto extends Omit<LabResultDto, "hasNote"> {
+  note: string | null;
+}
+
 export interface LabResultListResponse {
  results: LabResultDto[];
  meta: { total: number; limit: number; offset: number };
 }
+
+/** A user-scoped Biomarker catalog entry as the API serialises it. */
+export interface BiomarkerDto {
+  id: string;
+  name: string;
+  unit: string;
+  lowerBound: number | null;
+  upperBound: number | null;
+  panel: string | null;
+  hasContext: boolean;
+  context: string | null;
+  createdAt: string;
+  updatedAt: string;
+}
+
+export interface BiomarkerListResponse {
+  biomarkers: BiomarkerDto[];
+}
@@ -0,0 +1,63 @@
+import { describe, expect, it } from "vitest";
+
+import { groupRowsByAnalyte } from "../lab-biomarker-backfill";
+
+function row(
+  id: string,
+  analyte: string,
+  unit: string,
+  takenAt: string,
+  opts: { low?: number | null; high?: number | null; panel?: string | null } = {},
+) {
+  return {
+    id,
+    analyte,
+    unit,
+    referenceLow: opts.low ?? null,
+    referenceHigh: opts.high ?? null,
+    panel: opts.panel ?? null,
+    takenAt: new Date(takenAt),
+  };
+}
+
+describe("groupRowsByAnalyte", () => {
+  it("collapses case/spacing variants of the same analyte into one group", () => {
+    const groups = groupRowsByAnalyte([
+      row("a", "LDL", "mg/dL", "2026-01-01T00:00:00Z"),
+      row("b", "ldl", "mg/dl", "2026-02-01T00:00:00Z"),
+      row("c", " LDL ", "mg/dL", "2026-03-01T00:00:00Z"),
+    ]);
+    expect(groups).toHaveLength(1);
+    expect(groups[0].ids.sort()).toEqual(["a", "b", "c"]);
+  });
+
+  it("uses the most-recently-taken reading for the canonical name/unit/range", () => {
+    // Same analyte key ("ldl"), case + unit + range drift across reports —
+    // the newest report's spelling/unit/range wins.
+    const groups = groupRowsByAnalyte([
+      row("old", "ldl", "mg/dl", "2026-01-01T00:00:00Z", { high: 100 }),
+      row("new", "LDL", "mg/dL", "2026-06-01T00:00:00Z", { high: 116 }),
+    ]);
+    expect(groups).toHaveLength(1);
+    expect(groups[0].name).toBe("LDL");
+    expect(groups[0].unit).toBe("mg/dL");
+    expect(groups[0].referenceHigh).toBe(116);
+  });
+
+  it("keeps distinct analytes in separate groups", () => {
+    const groups = groupRowsByAnalyte([
+      row("a", "LDL", "mg/dL", "2026-01-01T00:00:00Z"),
+      row("b", "HDL", "mg/dL", "2026-01-01T00:00:00Z"),
+    ]);
+    expect(groups).toHaveLength(2);
+  });
+
+  it("skips a row with a blank analyte", () => {
+    const groups = groupRowsByAnalyte([
+      row("a", "   ", "mg/dL", "2026-01-01T00:00:00Z"),
+      row("b", "LDL", "mg/dL", "2026-01-01T00:00:00Z"),
+    ]);
+    expect(groups).toHaveLength(1);
+    expect(groups[0].name).toBe("LDL");
+  });
+});
@@ -0,0 +1,217 @@
+/**
+ * v1.18.1 — one-shot backfill that links legacy `LabResult` rows to a
+ * user-scoped `Biomarker` catalog entry.
+ *
+ * Before the catalog existed, every lab reading carried its own free-text
+ * `analyte` / `unit` / `reference*`. Recording "LDL" three times forked the
+ * "same" marker into "LDL" / "ldl" / "LDL-C" with possibly diverging units
+ * and ranges. This pass heals that at the source: for each user, it groups
+ * every un-linked live reading by `lower(analyte)`, creates ONE `Biomarker`
+ * per group (using the most-recently-taken reading's spelling / unit /
+ * reference bounds — "last lab report wins"), and stamps `biomarkerId` on
+ * every row in the group.
+ *
+ * Idempotent across reboots: the discovery predicate is "the user has at
+ * least one live reading with `biomarkerId IS NULL`". A completed pass leaves
+ * every reading linked, so the user drops out of the discovery set. A reboot
+ * mid-pass re-runs from scratch — `Biomarker` creation upserts on
+ * `(userId, name)` and the row-link `updateMany` is `biomarkerId: null`-gated,
+ * so the result converges. A reading whose marker already exists (e.g. the
+ * user defined it by hand) re-uses that row rather than minting a duplicate.
+ *
+ * Modelled on `sleep-timeline-backfill.ts` / `whoop-backfill.ts`. The queue
+ * name MUST be registered in `allQueues` in `src/lib/jobs/reminder-worker.ts`
+ * or pg-boss never provisions it and the boot enqueue silently never drains
+ * (the v1.4.37 dead-queue class).
+ */
+import { prisma } from "@/lib/db";
+import { getGlobalBoss } from "@/lib/jobs/boss-instance";
+import { annotate } from "@/lib/logging/context";
+
+export const LAB_BIOMARKER_BACKFILL_QUEUE = "lab-biomarker-backfill";
+
+/**
+ * Serial concurrency — the per-user pass is a short burst of grouped writes;
+ * concurrency-1 keeps it off the request pool, matching the other backfill
+ * queues.
+ */
+export const LAB_BIOMARKER_BACKFILL_CONCURRENCY = 1;
+
+export interface LabBiomarkerBackfillPayload {
+  userId: string;
+  enqueuedAt: string;
+}
+
+/** A single legacy reading the grouping reads. */
+interface LegacyRow {
+  id: string;
+  analyte: string;
+  unit: string;
+  referenceLow: number | null;
+  referenceHigh: number | null;
+  panel: string | null;
+  takenAt: Date;
+}
+
+interface AnalyteGroup {
+  /** Canonical spelling = the most-recently-taken reading's `analyte`. */
+  name: string;
+  unit: string;
+  referenceLow: number | null;
+  referenceHigh: number | null;
+  panel: string | null;
+  ids: string[];
+}
+
+/**
+ * Reduce the user's un-linked rows into one group per `lower(analyte)`. The
+ * canonical name / unit / range come from the most-recently-TAKEN reading in
+ * each group ("last lab report wins"); every row id rides into the group so a
+ * single `updateMany` can link them. Exported for unit testing.
+ */
+export function groupRowsByAnalyte(rows: LegacyRow[]): AnalyteGroup[] {
+  const byKey = new Map<string, LegacyRow[]>();
+  for (const r of rows) {
+    const key = r.analyte.trim().toLowerCase();
+    if (!key) continue;
+    const bucket = byKey.get(key);
+    if (bucket) bucket.push(r);
+    else byKey.set(key, [r]);
+  }
+
+  const groups: AnalyteGroup[] = [];
+  for (const bucket of byKey.values()) {
+    // Newest reading defines the canonical name / unit / range.
+    const newest = bucket.reduce((a, b) =>
+      b.takenAt.getTime() >= a.takenAt.getTime() ? b : a,
+    );
+    groups.push({
+      name: newest.analyte.trim(),
+      unit: newest.unit,
+      referenceLow: newest.referenceLow,
+      referenceHigh: newest.referenceHigh,
+      panel: newest.panel,
+      ids: bucket.map((r) => r.id),
+    });
+  }
+  return groups;
+}
+
+/**
+ * Backfill one user: group un-linked live readings, create/reuse a Biomarker
+ * per group, link the rows. Returns the count of markers touched + rows
+ * linked.
+ */
+export async function runLabBiomarkerBackfillForUser(
+  userId: string,
+): Promise<{ markers: number; linked: number }> {
+  const rows = await prisma.labResult.findMany({
+    where: { userId, deletedAt: null, biomarkerId: null },
+    select: {
+      id: true,
+      analyte: true,
+      unit: true,
+      referenceLow: true,
+      referenceHigh: true,
+      panel: true,
+      takenAt: true,
+    },
+  });
+
+  if (rows.length === 0) {
+    return { markers: 0, linked: 0 };
+  }
+
+  const groups = groupRowsByAnalyte(rows);
+
+  let markers = 0;
+  let linked = 0;
+  for (const group of groups) {
+    // Re-use a hand-defined marker of the same name if one exists; otherwise
+    // mint it. `(userId, name)` is unique, so a concurrent re-run converges.
+    const biomarker = await prisma.biomarker.upsert({
+      where: { userId_name: { userId, name: group.name } },
+      // An existing marker keeps its own (possibly user-tuned) unit / range.
+      update: {},
+      create: {
+        userId,
+        name: group.name,
+        unit: group.unit,
+        lowerBound: group.referenceLow,
+        upperBound: group.referenceHigh,
+        panel: group.panel,
+      },
+    });
+    markers += 1;
+
+    const { count } = await prisma.labResult.updateMany({
+      where: { id: { in: group.ids }, userId, biomarkerId: null },
+      data: { biomarkerId: biomarker.id },
+    });
+    linked += count;
+  }
+
+  annotate({
+    action: {
+      name: "labs.biomarker.backfill.complete",
+      details: { markers, linked },
+    },
+  });
+  return { markers, linked };
+}
+
+/**
+ * Boot-time discovery. Finds every user holding at least one un-linked live
+ * lab reading and enqueues one job each. Idempotent across reboots: a
+ * completed pass links every reading, dropping the user from the discovery
+ * set. `singletonKey` coalesces duplicate sends.
+ *
+ * Best-effort: errors come back through the result value so worker boot never
+ * fails because of a backfill miss.
+ */
+export async function enqueueBootTimeLabBiomarkerBackfill(): Promise<{
+  enqueued: number;
+  skipped: number;
+  error: string | null;
+}> {
+  const boss = getGlobalBoss();
+  if (!boss) {
+    return { enqueued: 0, skipped: 0, error: null };
+  }
+
+  try {
+    const rows = await prisma.labResult.findMany({
+      where: { deletedAt: null, biomarkerId: null },
+      select: { userId: true },
+      distinct: ["userId"],
+    });
+
+    if (rows.length === 0) {
+      return { enqueued: 0, skipped: 0, error: null };
+    }
+
+    let enqueued = 0;
+    let skipped = 0;
+    for (const { userId } of rows) {
+      const payload: LabBiomarkerBackfillPayload = {
+        userId,
+        enqueuedAt: new Date().toISOString(),
+      };
+      const jobId = await boss.send(LAB_BIOMARKER_BACKFILL_QUEUE, payload, {
+        retryLimit: 3,
+        retryDelay: 60,
+        retryBackoff: true,
+        singletonKey: `lab-biomarker-backfill|${userId}`,
+      });
+      if (jobId) enqueued += 1;
+      else skipped += 1;
+    }
+    return { enqueued, skipped, error: null };
+  } catch (err) {
+    return {
+      enqueued: 0,
+      skipped: 0,
+      error: err instanceof Error ? err.message : String(err),
+    };
+  }
+}
@@ -28,6 +28,13 @@ import {
  enqueueBootTimeSleepTimelineBackfill,
  type SleepTimelineBackfillPayload,
 } from "@/lib/jobs/sleep-timeline-backfill";
+import {
+  LAB_BIOMARKER_BACKFILL_QUEUE,
+  LAB_BIOMARKER_BACKFILL_CONCURRENCY,
+  runLabBiomarkerBackfillForUser,
+  enqueueBootTimeLabBiomarkerBackfill,
+  type LabBiomarkerBackfillPayload,
+} from "@/lib/jobs/lab-biomarker-backfill";
 import { reportWorkerError } from "@/lib/jobs/report-worker-error";
 import { markWorkerStarted, recordError } from "@/lib/jobs/worker-status";
 import { setGlobalBoss } from "@/lib/jobs/boss-instance";
@@ -662,6 +669,11 @@ export async function startReminderWorker() {
    // pg-boss never provisions it and the boot enqueue silently never drains
    // (the v1.4.37 dead-queue class).
    SLEEP_TIMELINE_BACKFILL_QUEUE,
+    // v1.18.1 — one-shot backfill that links legacy free-text lab readings to
+    // a user-scoped Biomarker catalog entry (group by `lower(analyte)`). The
+    // queue MUST be registered here or pg-boss never provisions it and the
+    // boot enqueue silently never drains (the v1.4.37 dead-queue class).
+    LAB_BIOMARKER_BACKFILL_QUEUE,
    // v1.17.0 — Nightscout CGM poll sync. Poll-only (no webhook, no OAuth, no
    // backfill queue — the hourly window walks the recent SGV set). The queue
    // MUST be registered here or pg-boss never provisions it and the schedule
@@ -1125,6 +1137,25 @@ export async function startReminderWorker() {
      }
    },
  );
+  // v1.18.1 — one-shot lab-biomarker backfill. The boot enqueue below sends
+  // one job per user holding un-linked free-text lab readings; this handler
+  // groups them by `lower(analyte)`, mints/reuses a Biomarker per group, and
+  // links the rows. Idempotent — a re-run links only what is still un-linked.
+  await boss.work<LabBiomarkerBackfillPayload>(
+    LAB_BIOMARKER_BACKFILL_QUEUE,
+    { localConcurrency: LAB_BIOMARKER_BACKFILL_CONCURRENCY },
+    async (jobs) => {
+      for (const job of jobs) {
+        const { userId } = job.data;
+        const { markers, linked } =
+          await runLabBiomarkerBackfillForUser(userId);
+        workerLog(
+          "info",
+          `[lab-biomarker-backfill] user=${userId} markers=${markers} linked=${linked}`,
+        );
+      }
+    },
+  );
  // v1.17.0 — Nightscout CGM poll-cohort sync. The hourly cron tick (no
  // `userId`) walks every configured instance; one user's unreachable host is
  // warned, not fatal.
@@ -1996,6 +2027,33 @@ export async function startReminderWorker() {
    );
  }

+  // v1.18.1 — fire-and-forget boot discovery for the one-shot lab-biomarker
+  // backfill. Finds every user holding an un-linked live lab reading and
+  // enqueues one job each. Idempotent across reboots: a completed pass links
+  // every reading, dropping the user from the discovery set. Errors come back
+  // through the helper's result value — worker boot never fails on a miss.
+  try {
+    const { enqueued, skipped, error } =
+      await enqueueBootTimeLabBiomarkerBackfill();
+    if (error) {
+      workerLog(
+        "error",
+        `[lab-biomarker-backfill] boot discovery failed: ${error}`,
+      );
+    } else {
+      workerLog(
+        "info",
+        `[lab-biomarker-backfill] boot discovery: enqueued=${enqueued} skipped=${skipped}`,
+      );
+    }
+  } catch (err) {
+    workerLog(
+      "error",
+      "[lab-biomarker-backfill] boot discovery threw an unexpected error",
+      err,
+    );
+  }
+
  // v1.7.0 — fire-and-forget boot discovery for the daily-mean
  // consolidation pass. Finds every user holding live per-sample
  // high-frequency mean-type rows and enqueues one job per account.
@@ -0,0 +1,35 @@
+import { beforeEach, describe, expect, it, vi } from "vitest";
+
+import { _resetCryptoCacheForTests } from "@/lib/crypto";
+
+import {
+  decryptContextFromBytes,
+  encryptContextToBytes,
+} from "../biomarker-store";
+
+const KEY =
+  "0123456789abcdef0123456789abcdef0123456789abcdef0123456789abcdef";
+
+describe("biomarker context codec", () => {
+  beforeEach(() => {
+    vi.unstubAllEnvs();
+    vi.stubEnv("ENCRYPTION_KEYS", "");
+    vi.stubEnv("ENCRYPTION_ACTIVE_KEY_ID", "");
+    vi.stubEnv("ENCRYPTION_KEY", KEY);
+    _resetCryptoCacheForTests();
+  });
+
+  it("round-trips a UTF-8 context note through Bytes", () => {
+    const plain = "Nüchtern · morgens · Lipidpanel";
+    const bytes = encryptContextToBytes(plain);
+    expect(bytes).toBeInstanceOf(Uint8Array);
+    expect(decryptContextFromBytes(bytes)).toBe(plain);
+  });
+
+  it("does not store the plaintext verbatim in the bytes", () => {
+    const plain = "secret context";
+    const bytes = encryptContextToBytes(plain);
+    const asString = Buffer.from(bytes).toString("utf8");
+    expect(asString).not.toContain(plain);
+  });
+});
@@ -0,0 +1,96 @@
+import { describe, expect, it } from "vitest";
+
+import {
+  resolveLabFields,
+  serialiseLabResult,
+  serialiseLabResultDetail,
+  type LabRow,
+  type ResolvedBiomarker,
+} from "../serialise";
+
+const baseRow: LabRow = {
+  id: "lr_1",
+  panel: "Legacy panel",
+  analyte: "ldl", // lowercase legacy spelling
+  value: 130,
+  unit: "mg/dl", // lowercase legacy unit
+  referenceLow: null,
+  referenceHigh: 100, // stale per-row bound
+  takenAt: new Date("2026-01-01T08:00:00.000Z"),
+  source: "MANUAL",
+  biomarkerId: "bm_1",
+  noteEncrypted: null,
+  createdAt: new Date("2026-01-01T08:00:00.000Z"),
+  updatedAt: new Date("2026-01-01T08:00:00.000Z"),
+};
+
+const biomarker: ResolvedBiomarker = {
+  id: "bm_1",
+  name: "LDL Cholesterol",
+  unit: "mg/dL",
+  lowerBound: null,
+  upperBound: 116,
+  panel: "Lipids",
+};
+
+describe("resolveLabFields", () => {
+  it("prefers the linked biomarker over the legacy row fields", () => {
+    const r = resolveLabFields(baseRow, biomarker);
+    expect(r.analyte).toBe("LDL Cholesterol");
+    expect(r.unit).toBe("mg/dL");
+    expect(r.referenceHigh).toBe(116);
+    expect(r.panel).toBe("Lipids");
+  });
+
+  it("falls back to the row fields when unlinked", () => {
+    const r = resolveLabFields({ ...baseRow, biomarkerId: null }, null);
+    expect(r.analyte).toBe("ldl");
+    expect(r.unit).toBe("mg/dl");
+    expect(r.referenceHigh).toBe(100);
+    expect(r.panel).toBe("Legacy panel");
+  });
+});
+
+describe("serialiseLabResult", () => {
+  it("computes the verdict from the RESOLVED catalog bounds, not the stale row", () => {
+    // value 130 vs row's stale high 100 → would be 'above';
+    // vs catalog high 116 → still 'above', but the resolved bound is what counts.
+    const dto = serialiseLabResult(baseRow, biomarker);
+    expect(dto.unit).toBe("mg/dL");
+    expect(dto.referenceHigh).toBe(116);
+    expect(dto.rangeStatus).toBe("above");
+    expect(dto.biomarkerId).toBe("bm_1");
+    expect(dto.hasNote).toBe(false);
+  });
+
+  it("in-range when the resolved catalog band contains the value", () => {
+    const within = serialiseLabResult({ ...baseRow, value: 90 }, biomarker);
+    expect(within.rangeStatus).toBe("in-range");
+  });
+
+  it("uses legacy fields and verdict when unlinked", () => {
+    const dto = serialiseLabResult({ ...baseRow, biomarkerId: null }, null);
+    expect(dto.unit).toBe("mg/dl");
+    // 130 > row high 100 → above
+    expect(dto.rangeStatus).toBe("above");
+    expect(dto.biomarkerId).toBeNull();
+  });
+
+  it("flags an encrypted note without echoing it", () => {
+    const dto = serialiseLabResult(
+      { ...baseRow, noteEncrypted: new Uint8Array([1, 2, 3]) },
+      biomarker,
+    );
+    expect(dto.hasNote).toBe(true);
+    expect(dto).not.toHaveProperty("noteEncrypted");
+  });
+});
+
+describe("serialiseLabResultDetail", () => {
+  it("carries the decrypted note in place of hasNote", () => {
+    const dto = serialiseLabResultDetail(baseRow, biomarker, "fasting sample");
+    expect(dto.note).toBe("fasting sample");
+    expect(dto).not.toHaveProperty("hasNote");
+    expect(dto.unit).toBe("mg/dL");
+  });
+});
@@ -0,0 +1,87 @@
+/**
+ * v1.18.1 — static seed catalog of common blood/lab biomarkers.
+ *
+ * This is NOT a DB table. It is a curated list offered at the add step
+ * ("pick a common marker, or create your own") so a self-hoster does not
+ * type a marker definition from scratch. Selecting a seed pre-fills the
+ * inline definition form (canonical name, unit, suggested reference bounds)
+ * which the user then accepts or overrides before it becomes a real,
+ * user-scoped `Biomarker` row.
+ *
+ * The suggested ranges are EDITABLE DEFAULTS, never gospel — reference
+ * windows vary by lab, sex, and age. The display name is localised via the
+ * `labs.catalog.<slug>` i18n key; the EN slug is the stable identity (mirrors
+ * the Insights slug/alias pattern). Units stay literal (mg/dL etc. are not
+ * translated).
+ *
+ * Source ranges: common adult fasting reference windows (US conventional
+ * units where the metric/SI split matters). Presented as starting points.
+ */
+
+export interface BiomarkerSeed {
+  /** Stable EN identity; the `labs.catalog.<slug>` i18n key resolves the name. */
+  slug: string;
+  /** Panel grouping key; the `labs.catalog.panel.<panel>` i18n key labels it. */
+  panel: string;
+  /** Canonical unit for every reading against this marker. */
+  unit: string;
+  /** Suggested lower bound (editable default), or null when open-ended. */
+  lowerBound: number | null;
+  /** Suggested upper bound (editable default), or null when open-ended. */
+  upperBound: number | null;
+}
+
+export const BIOMARKER_CATALOG: readonly BiomarkerSeed[] = [
+  // Lipids
+  { slug: "total-cholesterol", panel: "lipids", unit: "mg/dL", lowerBound: null, upperBound: 200 },
+  { slug: "ldl", panel: "lipids", unit: "mg/dL", lowerBound: null, upperBound: 116 },
+  { slug: "hdl", panel: "lipids", unit: "mg/dL", lowerBound: 40, upperBound: null },
+  { slug: "triglycerides", panel: "lipids", unit: "mg/dL", lowerBound: null, upperBound: 150 },
+  // Glucose metabolism
+  { slug: "fasting-glucose", panel: "glucose", unit: "mg/dL", lowerBound: 70, upperBound: 100 },
+  { slug: "hba1c", panel: "glucose", unit: "%", lowerBound: null, upperBound: 5.7 },
+  // Thyroid
+  { slug: "tsh", panel: "thyroid", unit: "mIU/L", lowerBound: 0.4, upperBound: 4 },
+  { slug: "ft3", panel: "thyroid", unit: "pg/mL", lowerBound: 2.3, upperBound: 4.2 },
+  { slug: "ft4", panel: "thyroid", unit: "ng/dL", lowerBound: 0.8, upperBound: 1.8 },
+  // Iron
+  { slug: "ferritin", panel: "iron", unit: "ng/mL", lowerBound: 30, upperBound: 400 },
+  { slug: "transferrin-saturation", panel: "iron", unit: "%", lowerBound: 20, upperBound: 50 },
+  // Vitamins
+  { slug: "vitamin-d", panel: "vitamins", unit: "ng/mL", lowerBound: 30, upperBound: 100 },
+  { slug: "vitamin-b12", panel: "vitamins", unit: "pg/mL", lowerBound: 200, upperBound: 900 },
+  { slug: "folate", panel: "vitamins", unit: "ng/mL", lowerBound: 3, upperBound: 20 },
+  // Inflammation
+  { slug: "hs-crp", panel: "inflammation", unit: "mg/L", lowerBound: null, upperBound: 3 },
+  // Renal
+  { slug: "creatinine", panel: "renal", unit: "mg/dL", lowerBound: 0.6, upperBound: 1.3 },
+  { slug: "egfr", panel: "renal", unit: "mL/min/1.73m²", lowerBound: 90, upperBound: null },
+  // Liver
+  { slug: "alt", panel: "liver", unit: "U/L", lowerBound: null, upperBound: 40 },
+  { slug: "ast", panel: "liver", unit: "U/L", lowerBound: null, upperBound: 40 },
+  { slug: "ggt", panel: "liver", unit: "U/L", lowerBound: null, upperBound: 55 },
+  // Electrolytes
+  { slug: "sodium", panel: "electrolytes", unit: "mmol/L", lowerBound: 135, upperBound: 145 },
+  { slug: "potassium", panel: "electrolytes", unit: "mmol/L", lowerBound: 3.5, upperBound: 5.1 },
+  // Blood count
+  { slug: "hemoglobin", panel: "bloodCount", unit: "g/dL", lowerBound: 12, upperBound: 17.5 },
+  { slug: "hematocrit", panel: "bloodCount", unit: "%", lowerBound: 36, upperBound: 50 },
+  { slug: "wbc", panel: "bloodCount", unit: "10³/µL", lowerBound: 4, upperBound: 11 },
+  { slug: "platelets", panel: "bloodCount", unit: "10³/µL", lowerBound: 150, upperBound: 400 },
+] as const;
+
+/** The set of panel keys present in the catalog, in display order. */
+export const BIOMARKER_PANELS = [
+  "lipids",
+  "glucose",
+  "thyroid",
+  "iron",
+  "vitamins",
+  "inflammation",
+  "renal",
+  "liver",
+  "electrolytes",
+  "bloodCount",
+] as const;
+
+export type BiomarkerPanelKey = (typeof BIOMARKER_PANELS)[number];
@@ -0,0 +1,30 @@
+/**
+ * v1.18.1 — server-side helpers for the user-scoped Biomarker catalog.
+ *
+ * The AES-256-GCM ↔ `Bytes` codec for `Biomarker.contextEncrypted`. The
+ * per-marker context note ("what this means") is the only sensitive column on
+ * the model; it shares the `encrypt()` string format (`"<keyId>.<base64>"`)
+ * every other `*Encrypted` column uses, encoded as UTF-8 bytes.
+ *
+ * Mirrors the `LabResult.noteEncrypted` codec in `./store.ts` so the two
+ * encrypted columns on the Labs feature share one byte layout.
+ */
+import { Buffer } from "node:buffer";
+
+import { decrypt, encrypt } from "@/lib/crypto";
+
+/** Encrypt a UTF-8 context note into the `Bytes` payload the schema stores. */
+export function encryptContextToBytes(
+  plaintext: string,
+): Uint8Array<ArrayBuffer> {
+  const ciphertext = encrypt(plaintext);
+  const encoded = Buffer.from(ciphertext, "utf8");
+  const out = new Uint8Array(new ArrayBuffer(encoded.byteLength));
+  out.set(encoded);
+  return out;
+}
+
+/** Decrypt a stored `Bytes` context note back to plaintext. */
+export function decryptContextFromBytes(buf: Uint8Array): string {
+  return decrypt(Buffer.from(buf).toString("utf8"));
+}
@@ -0,0 +1,13 @@
+/**
+ * v1.18.1 — shared lab-value number formatting.
+ *
+ * The list card, the detail history rows, and the chart tooltip all trim a
+ * lab reading the same way: whole numbers render bare, fractional values keep
+ * up to two decimals (no trailing-zero noise). Centralised so the three
+ * surfaces stay byte-identical.
+ */
+export function formatLabValue(value: number): string {
+  return Number.isInteger(value)
+    ? String(value)
+    : String(Number(value.toFixed(2)));
+}
@@ -0,0 +1,150 @@
+/**
+ * v1.18.1 — server-authoritative lab-result DTO resolution.
+ *
+ * A lab row resolves its display name + unit + reference bounds in ONE place:
+ *
+ *  - If the row links a `Biomarker` (`biomarkerId` set), the canonical name,
+ *    unit, and reference bounds come FROM THE BIOMARKER. The per-row legacy
+ *    `analyte` / `unit` / `reference*` columns are ignored — they are stale
+ *    historical truth at that point.
+ *  - If the row is unlinked (legacy / pre-backfill), it falls back to its own
+ *    free-text `analyte` / `unit` / `reference*` columns.
+ *
+ * Either way the verdict (`rangeStatus`) is computed from the RESOLVED bounds
+ * via `classifyReferenceRange`. The DTO carries the resolved values so the web
+ * client AND the iOS client render the same numbers — neither recomputes the
+ * range or guesses the unit. This is the server-authoritative-parity rule for
+ * Labs.
+ */
+import { classifyReferenceRange } from "@/lib/labs/reference-range";
+
+/** The minimal biomarker shape the resolver needs (no encrypted context). */
+export interface ResolvedBiomarker {
+  id: string;
+  name: string;
+  unit: string;
+  lowerBound: number | null;
+  upperBound: number | null;
+  panel: string | null;
+}
+
+/** The lab-result row shape the resolver reads (Prisma row subset). */
+export interface LabRow {
+  id: string;
+  panel: string | null;
+  analyte: string;
+  value: number;
+  unit: string;
+  referenceLow: number | null;
+  referenceHigh: number | null;
+  takenAt: Date;
+  source: string;
+  biomarkerId: string | null;
+  noteEncrypted: Uint8Array | null;
+  createdAt: Date;
+  updatedAt: Date;
+}
+
+/**
+ * Resolve the canonical name / unit / bounds / panel for a lab row, preferring
+ * the linked biomarker over the legacy per-row fields. Returns a plain shape
+ * the list + detail serialisers both build on.
+ */
+export function resolveLabFields(
+  row: Pick<
+    LabRow,
+    | "analyte"
+    | "unit"
+    | "referenceLow"
+    | "referenceHigh"
+    | "panel"
+    | "biomarkerId"
+  >,
+  biomarker: ResolvedBiomarker | null | undefined,
+): {
+  analyte: string;
+  unit: string;
+  referenceLow: number | null;
+  referenceHigh: number | null;
+  panel: string | null;
+} {
+  if (biomarker) {
+    return {
+      analyte: biomarker.name,
+      unit: biomarker.unit,
+      referenceLow: biomarker.lowerBound,
+      referenceHigh: biomarker.upperBound,
+      panel: biomarker.panel,
+    };
+  }
+  return {
+    analyte: row.analyte,
+    unit: row.unit,
+    referenceLow: row.referenceLow,
+    referenceHigh: row.referenceHigh,
+    panel: row.panel,
+  };
+}
+
+/**
+ * Serialise a lab row to the list DTO — never echoes the encrypted note bytes
+ * (only the `hasNote` flag) and resolves name/unit/range server-side.
+ */
+export function serialiseLabResult(
+  row: LabRow,
+  biomarker?: ResolvedBiomarker | null,
+) {
+  const resolved = resolveLabFields(row, biomarker);
+  return {
+    id: row.id,
+    biomarkerId: row.biomarkerId,
+    panel: resolved.panel,
+    analyte: resolved.analyte,
+    value: row.value,
+    unit: resolved.unit,
+    referenceLow: resolved.referenceLow,
+    referenceHigh: resolved.referenceHigh,
+    takenAt: row.takenAt.toISOString(),
+    source: row.source,
+    hasNote: row.noteEncrypted !== null,
+    rangeStatus: classifyReferenceRange(
+      row.value,
+      resolved.referenceLow,
+      resolved.referenceHigh,
+    ),
+    createdAt: row.createdAt.toISOString(),
+    updatedAt: row.updatedAt.toISOString(),
+  };
+}
+
+/**
+ * Serialise a lab row to the detail DTO — same as the list DTO but carries the
+ * decrypted `note` instead of the `hasNote` flag.
+ */
+export function serialiseLabResultDetail(
+  row: LabRow,
+  biomarker: ResolvedBiomarker | null | undefined,
+  note: string | null,
+) {
+  const resolved = resolveLabFields(row, biomarker);
+  return {
+    id: row.id,
+    biomarkerId: row.biomarkerId,
+    panel: resolved.panel,
+    analyte: resolved.analyte,
+    value: row.value,
+    unit: resolved.unit,
+    referenceLow: resolved.referenceLow,
+    referenceHigh: resolved.referenceHigh,
+    takenAt: row.takenAt.toISOString(),
+    source: row.source,
+    note,
+    rangeStatus: classifyReferenceRange(
+      row.value,
+      resolved.referenceLow,
+      resolved.referenceHigh,
+    ),
+    createdAt: row.createdAt.toISOString(),
+    updatedAt: row.updatedAt.toISOString(),
+  };
+}
@@ -0,0 +1,182 @@
+/**
+ * OpenAPI route table for the user-scoped Biomarker catalog (`/api/biomarkers`).
+ *
+ * Part of the OpenAPI route table; aggregated in `./index.ts`. The request
+ * bodies reuse the runtime Zod schemas from `@/lib/validations/biomarkers`
+ * so the wire contract stays single-source. The response shape is declared
+ * here (the route serialises a derived `hasContext` flag the input schema
+ * doesn't carry, and returns the decrypted `context`).
+ *
+ * The iOS client consumes the biomarker DTO + the `biomarkerId` field on
+ * `LabResult` to render the resolved unit + reference range without
+ * recomputing — server-authoritative parity for Labs.
+ */
+import type { ZodOpenApiObject } from "zod-openapi";
+import { z } from "zod/v4";
+
+import {
+  createBiomarkerSchema,
+  updateBiomarkerSchema,
+} from "@/lib/validations/biomarkers";
+
+import { dataEnvelope, errorEnvelope, stdResponses } from "./shared";
+
+createBiomarkerSchema.meta({
+  id: "CreateBiomarkerRequest",
+  description:
+    "Define a user-scoped biomarker ONCE: canonical `name`, `unit`, optional reference bounds (`lowerBound` / `upperBound`; when both present `lowerBound` must not exceed `upperBound`), an optional encrypted `context` note, and an optional `panel` grouping. The name is unique per user (no second 'LDL'). Recording a value later just picks this marker — its unit + range are never re-entered.",
+});
+
+updateBiomarkerSchema.meta({
+  id: "UpdateBiomarkerRequest",
+  description:
+    "Partial edit of a biomarker. An omitted key leaves the column untouched; an explicit `null` on `context` / `panel` / a bound clears it. A rename that collides with another of the caller's markers is rejected 409.",
+});
+
+const biomarkerRow = z
+  .object({
+    id: z.string(),
+    name: z.string(),
+    unit: z.string(),
+    lowerBound: z.number().nullable(),
+    upperBound: z.number().nullable(),
+    panel: z.string().nullable(),
+    hasContext: z.boolean(),
+    context: z.string().nullable(),
+    createdAt: z.string(),
+    updatedAt: z.string(),
+  })
+  .meta({
+    id: "Biomarker",
+    description:
+      "A user-scoped catalog marker. `context` is the decrypted per-marker note (or null); `hasContext` flags its presence. A `LabResult` linking this marker resolves its unit + reference bounds from here.",
+  });
+
+const listResponse = z
+  .object({ biomarkers: z.array(biomarkerRow) })
+  .meta({ id: "ListBiomarkersResponse" });
+
+const conflict = {
+  "409": {
+    description: "A biomarker with this name already exists for the caller.",
+    content: { "application/json": { schema: errorEnvelope } },
+  },
+};
+
+const notFound = {
+  "404": {
+    description: "Biomarker not found (or owned by another user).",
+    content: { "application/json": { schema: errorEnvelope } },
+  },
+};
+
+export const biomarkerPaths: NonNullable<ZodOpenApiObject["paths"]> = {
+  "/api/biomarkers": {
+    get: {
+      tags: ["Labs"],
+      summary: "List the caller's biomarker catalog",
+      description:
+        "Returns every biomarker the caller has defined, name-ordered. Each carries its unit, reference bounds, and decrypted context.",
+      responses: {
+        "200": {
+          description: "Biomarker catalog.",
+          content: {
+            "application/json": {
+              schema: dataEnvelope(listResponse, "ListBiomarkersEnvelope"),
+            },
+          },
+        },
+        ...stdResponses,
+      },
+    },
+    post: {
+      tags: ["Labs"],
+      summary: "Define a biomarker",
+      description:
+        "Creates a user-scoped biomarker. The optional context note is AES-256-GCM encrypted before write. Audits as `biomarker.create`.",
+      requestBody: {
+        required: true,
+        content: { "application/json": { schema: createBiomarkerSchema } },
+      },
+      responses: {
+        "201": {
+          description: "Created biomarker.",
+          content: {
+            "application/json": {
+              schema: dataEnvelope(biomarkerRow, "CreateBiomarkerResponse"),
+            },
+          },
+        },
+        ...conflict,
+        ...stdResponses,
+      },
+    },
+  },
+  "/api/biomarkers/{id}": {
+    get: {
+      tags: ["Labs"],
+      summary: "Fetch a single biomarker",
+      description:
+        "Returns the biomarker including its decrypted `context`. Cross-user rows surface as 404.",
+      requestParams: { path: z.object({ id: z.string() }) },
+      responses: {
+        "200": {
+          description: "Biomarker detail.",
+          content: {
+            "application/json": {
+              schema: dataEnvelope(biomarkerRow, "GetBiomarkerResponse"),
+            },
+          },
+        },
+        ...notFound,
+        ...stdResponses,
+      },
+    },
+    put: {
+      tags: ["Labs"],
+      summary: "Edit a biomarker",
+      description:
+        "Partial edit; omitted fields are untouched, an explicit null clears `context` / `panel` / a bound. Audits as `biomarker.update`.",
+      requestParams: { path: z.object({ id: z.string() }) },
+      requestBody: {
+        required: true,
+        content: { "application/json": { schema: updateBiomarkerSchema } },
+      },
+      responses: {
+        "200": {
+          description: "Updated biomarker.",
+          content: {
+            "application/json": {
+              schema: dataEnvelope(biomarkerRow, "UpdateBiomarkerResponse"),
+            },
+          },
+        },
+        ...conflict,
+        ...notFound,
+        ...stdResponses,
+      },
+    },
+    delete: {
+      tags: ["Labs"],
+      summary: "Delete a biomarker",
+      description:
+        "Hard-deletes the catalog definition. The `onDelete: SetNull` FK unlinks every reading (they keep their legacy `analyte` / `unit`), so the history survives. Audits as `biomarker.delete`.",
+      requestParams: { path: z.object({ id: z.string() }) },
+      responses: {
+        "200": {
+          description: "Deletion succeeded.",
+          content: {
+            "application/json": {
+              schema: dataEnvelope(
+                z.object({ deleted: z.boolean() }),
+                "DeleteBiomarkerResponse",
+              ),
+            },
+          },
+        },
+        ...notFound,
+        ...stdResponses,
+      },
+    },
+  },
+};
@@ -26,6 +26,7 @@ import { authPaths } from "./auth";
 import { coachFeedbackPaths, coachPaths } from "./coach";
 import { consentPaths } from "./consent";
 import { cyclePaths } from "./cycle";
+import { biomarkerPaths } from "./biomarkers";
 import { devicePaths } from "./devices";
 import { healthRecordPaths } from "./health-record";
 import { importPaths } from "./import";
@@ -63,6 +64,7 @@ export const openApiPaths: NonNullable<ZodOpenApiObject["paths"]> = {
  ...importPaths,
  ...measurementReminderPaths,
  ...labsPaths,
+  ...biomarkerPaths,
 };

 export const openApiComponents: NonNullable<ZodOpenApiObject["components"]> = {
@@ -47,6 +47,7 @@ const rangeStatusEnum = z
 const labResultRow = z
  .object({
    id: z.string(),
+    biomarkerId: z.string().nullable(),
    panel: z.string().nullable(),
    analyte: z.string(),
    value: z.number(),
@@ -63,7 +64,7 @@ const labResultRow = z
  .meta({
    id: "LabResult",
    description:
-      "A stored lab result. The encrypted note is never echoed in list rows; `hasNote` flags its presence and the single-resource GET returns the decrypted `note`.",
+      "A stored lab result. `biomarkerId` links the user-scoped catalog marker (null for legacy free-text rows); when linked, `analyte` / `unit` / `referenceLow` / `referenceHigh` are RESOLVED server-side from the Biomarker — the client renders them and never recomputes the range. The encrypted note is never echoed in list rows; `hasNote` flags its presence and the single-resource GET returns the decrypted `note`.",
  });

 const labResultDetail = labResultRow
@@ -201,4 +202,36 @@ export const labsPaths: NonNullable<ZodOpenApiObject["paths"]> = {
      },
    },
  },
+  "/api/labs/restore": {
+    post: {
+      tags: ["Labs"],
+      summary: "Restore soft-deleted lab results",
+      description:
+        "Un-tombstones 1..200 of the caller's soft-deleted lab results in one pass (the delete-Undo affordance). A foreign / live id is a silent no-op. Audits via the wide-event ledger.",
+      requestBody: {
+        required: true,
+        content: {
+          "application/json": {
+            schema: z
+              .object({ ids: z.array(z.string()).min(1).max(200) })
+              .meta({ id: "RestoreLabResultsRequest" }),
+          },
+        },
+      },
+      responses: {
+        "200": {
+          description: "Restore count.",
+          content: {
+            "application/json": {
+              schema: dataEnvelope(
+                z.object({ restored: z.number() }),
+                "RestoreLabResultsResponse",
+              ),
+            },
+          },
+        },
+        ...stdResponses,
+      },
+    },
+  },
 };
@@ -9,6 +9,7 @@ export const labKeys = {
  labResults: () => ["lab-results"] as const,

  labResultsList: (params: {
+    biomarkerId?: string | undefined;
    analyte: string | undefined;
    panel: string | undefined;
    from: string | undefined;
@@ -19,6 +20,7 @@ export const labKeys = {
    [
      "lab-results",
      "list",
+      params.biomarkerId ?? null,
      params.analyte ?? null,
      params.panel ?? null,
      params.from ?? null,
@@ -26,4 +28,9 @@ export const labKeys = {
      params.page,
      params.sortDir,
    ] as const,
+
+  // v1.18.1 — user-scoped Biomarker catalog. The list feeds the picker and
+  // the manager; both invalidate `biomarkers()` after a mutation.
+  biomarkers: () => ["biomarkers"] as const,
+  biomarkerDetail: (id: string) => ["biomarkers", "detail", id] as const,
 };
@@ -0,0 +1,78 @@
+import { describe, expect, it } from "vitest";
+
+import {
+  createBiomarkerSchema,
+  updateBiomarkerSchema,
+} from "../biomarkers";
+
+describe("createBiomarkerSchema", () => {
+  it("accepts a minimal marker (name + unit only)", () => {
+    const r = createBiomarkerSchema.safeParse({ name: "LDL", unit: "mg/dL" });
+    expect(r.success).toBe(true);
+  });
+
+  it("accepts both bounds when low <= high", () => {
+    const r = createBiomarkerSchema.safeParse({
+      name: "Fasting glucose",
+      unit: "mg/dL",
+      lowerBound: 70,
+      upperBound: 100,
+    });
+    expect(r.success).toBe(true);
+  });
+
+  it("accepts an open-ended upper bound (lower omitted)", () => {
+    const r = createBiomarkerSchema.safeParse({
+      name: "LDL",
+      unit: "mg/dL",
+      upperBound: 116,
+    });
+    expect(r.success).toBe(true);
+  });
+
+  it("rejects a transposed range (low > high)", () => {
+    const r = createBiomarkerSchema.safeParse({
+      name: "LDL",
+      unit: "mg/dL",
+      lowerBound: 200,
+      upperBound: 100,
+    });
+    expect(r.success).toBe(false);
+  });
+
+  it("rejects an empty name", () => {
+    const r = createBiomarkerSchema.safeParse({ name: "  ", unit: "mg/dL" });
+    expect(r.success).toBe(false);
+  });
+
+  it("normalises an empty context to undefined", () => {
+    const r = createBiomarkerSchema.safeParse({
+      name: "TSH",
+      unit: "mIU/L",
+      context: "",
+    });
+    expect(r.success).toBe(true);
+    if (r.success) expect(r.data.context).toBeUndefined();
+  });
+});
+
+describe("updateBiomarkerSchema", () => {
+  it("accepts a partial edit", () => {
+    const r = updateBiomarkerSchema.safeParse({ unit: "mmol/L" });
+    expect(r.success).toBe(true);
+  });
+
+  it("accepts an explicit null to clear a bound", () => {
+    const r = updateBiomarkerSchema.safeParse({ lowerBound: null });
+    expect(r.success).toBe(true);
+    if (r.success) expect(r.data.lowerBound).toBeNull();
+  });
+
+  it("still rejects a transposed range on update", () => {
+    const r = updateBiomarkerSchema.safeParse({
+      lowerBound: 10,
+      upperBound: 5,
+    });
+    expect(r.success).toBe(false);
+  });
+});
@@ -75,6 +75,32 @@ describe("createLabResultSchema", () => {
    expect(r.success).toBe(true);
  });

+  it("accepts a structured entry (biomarkerId, no analyte/unit)", () => {
+    const r = createLabResultSchema.safeParse({
+      biomarkerId: "bm_123",
+      value: 110,
+      takenAt: RECENT,
+    });
+    expect(r.success).toBe(true);
+  });
+
+  it("rejects an entry with neither biomarkerId nor analyte", () => {
+    const r = createLabResultSchema.safeParse({
+      value: 110,
+      takenAt: RECENT,
+    });
+    expect(r.success).toBe(false);
+  });
+
+  it("rejects a free-text entry missing the unit", () => {
+    const r = createLabResultSchema.safeParse({
+      analyte: "LDL",
+      value: 110,
+      takenAt: RECENT,
+    });
+    expect(r.success).toBe(false);
+  });
+
  it("normalises an empty-string panel to undefined", () => {
    const r = createLabResultSchema.safeParse({
      analyte: "TSH",
@@ -0,0 +1,89 @@
+/**
+ * v1.18.1 — user-scoped Biomarker catalog validation.
+ *
+ * A `Biomarker` defines a lab marker ONCE: canonical name, unit, reference
+ * bounds, and an optional context note. Recording a value later is just
+ * picking the biomarker — the unit and reference range are resolved
+ * server-side from the catalog row, never re-entered (ending the per-row
+ * free-text divergence: "LDL" vs "ldl", `mg/dL` vs `mg/dl`).
+ *
+ * The reference window is the lab/sex/age-dependent "normal" range; the
+ * server's neutral range verdict (`classifyReferenceRange`) is computed
+ * against these bounds. Both are independently optional (a marker may report
+ * only an upper bound, e.g. LDL < 116); when both are present the lower must
+ * not exceed the upper.
+ */
+import { z } from "zod/v4";
+
+const requiredText = (max: number) => z.string().trim().min(1).max(max);
+
+const lowerBound = z.number().finite().optional();
+const upperBound = z.number().finite().optional();
+
+const optionalContext = z
+  .string()
+  .trim()
+  .max(2000)
+  .optional()
+  // An empty / whitespace-only context normalises to "no context" so a
+  // blank field clears rather than stores an empty string.
+  .transform((v) => (v && v.length > 0 ? v : undefined));
+
+const optionalPanel = z
+  .string()
+  .trim()
+  .min(1)
+  .max(120)
+  .optional()
+  .or(z.literal("").transform(() => undefined));
+
+export const createBiomarkerSchema = z
+  .object({
+    name: requiredText(120),
+    unit: requiredText(40),
+    lowerBound,
+    upperBound,
+    context: optionalContext,
+    panel: optionalPanel,
+  })
+  .refine(
+    (d) =>
+      d.lowerBound === undefined ||
+      d.upperBound === undefined ||
+      d.lowerBound <= d.upperBound,
+    {
+      message: "lowerBound must not exceed upperBound",
+      path: ["lowerBound"],
+    },
+  );
+
+export type CreateBiomarkerInput = z.infer<typeof createBiomarkerSchema>;
+
+/**
+ * Update schema: every field optional (partial edit). `context` / `panel` /
+ * a bound accept an explicit `null` to clear the stored value — distinct from
+ * an omitted key, which leaves the column untouched.
+ */
+export const updateBiomarkerSchema = z
+  .object({
+    name: requiredText(120).optional(),
+    unit: requiredText(40).optional(),
+    lowerBound: lowerBound.or(z.null()),
+    upperBound: upperBound.or(z.null()),
+    context: optionalContext.or(z.null()),
+    panel: optionalPanel.or(z.null()),
+  })
+  .refine(
+    (d) =>
+      d.lowerBound === undefined ||
+      d.lowerBound === null ||
+      d.upperBound === undefined ||
+      d.upperBound === null ||
+      d.lowerBound <= d.upperBound,
+    {
+      message: "lowerBound must not exceed upperBound",
+      path: ["lowerBound"],
+    },
+  );
+
+export type UpdateBiomarkerInput = z.infer<typeof updateBiomarkerSchema>;
@@ -68,17 +68,38 @@ const optionalNote = z
 const referenceLow = z.number().finite().optional();
 const referenceHigh = z.number().finite().optional();

+/**
+ * v1.18.1 — optional link to a user-scoped `Biomarker` (the catalog row).
+ * When set, the structured-entry path resolves the unit + reference range
+ * from the biomarker server-side, so `analyte` / `unit` may be omitted (the
+ * route fills them from the catalog row). A free-text reading without a
+ * catalog link stays valid (quick-capture / legacy path).
+ */
+const biomarkerId = z.string().trim().min(1).max(64).optional();
+
 export const createLabResultSchema = z
  .object({
+    biomarkerId,
    panel: optionalPanel,
-    analyte: requiredText(120),
+    analyte: requiredText(120).optional(),
    value: z.number().finite(),
-    unit: requiredText(40),
+    unit: requiredText(40).optional(),
    referenceLow,
    referenceHigh,
    takenAt: takenAtField,
    note: optionalNote,
  })
+  // Either a catalog link OR a free-text analyte must be present.
+  .refine((d) => d.biomarkerId !== undefined || d.analyte !== undefined, {
+    message: "Either biomarkerId or analyte is required",
+    path: ["analyte"],
+  })
+  // Without a catalog link the unit is required (the catalog otherwise
+  // supplies it server-side).
+  .refine((d) => d.biomarkerId !== undefined || d.unit !== undefined, {
+    message: "unit is required when no biomarkerId is given",
+    path: ["unit"],
+  })
  .refine(
    (d) =>
      d.referenceLow === undefined ||
@@ -123,8 +144,10 @@ export const updateLabResultSchema = z

 export type UpdateLabResultInput = z.infer<typeof updateLabResultSchema>;

-/** List query: filter by analyte (exact) + date range, paginate. */
+/** List query: filter by biomarker / analyte (exact) + date range, paginate. */
 export const listLabResultsSchema = z.object({
+  // v1.18.1 — filter to one catalog marker's readings (the detail chart feed).
+  biomarkerId: z.string().trim().min(1).max(64).optional(),
  analyte: z.string().trim().min(1).max(120).optional(),
  panel: z.string().trim().min(1).max(120).optional(),
  from: z