The automatic Newey-West rule gives a lag of 3 on 30 to 270 daily
values, which leaves most of a physiological series' carry-over out of
the intervals. The lag is now at least 7. Reference values are
recomputed with statsmodels at the new default, and the lag-3 values
stay pinned with an explicit lag. A fit whose residual autocorrelation
exceeds 0.5 is flagged, and the card, the clinician view and the PDF
say the ranges may still be too narrow.
The efficacy tab keeps its before/after comparison and gains, per metric
target, the level change and the change in weekly trend at the start,
each with a 95 % interval. The fit covers up to 90 days before and 180
after the start and ends before the first dose change. After the start,
days are left out when fewer than 80 % of the doses of the preceding 14
days were taken (cadence-aware, from the dose ledger) or when the
medication was paused or between courses. Other medications that
started, stopped, changed dose or paused inside the window are listed.
Below 14 days with readings across 21 days on either side the view says
what is missing instead of showing numbers.
The efficacy response gains a nullable segmented block per target.
Per-medication effect view: plots the target metric/lab with start, dose
changes, and pauses marked, a before/after-start comparison, and adherence
overlaid — descriptive only, never a verdict or dose advice. Compact summary on
the medication insights area. Target resolved from ATC class or name, with a
per-user override. Migration 0232.
Add the migration (0232), Prisma model MedicationEfficacyTarget (persists ONLY
the user's explicit target override; everything else derives each read), and
the server builder buildMedicationEfficacy that composes the target's series,
a before/after-start comparison, the cadence-aware adherence lane (never
recomputed), an optional conservative level-shift note, honest data-floor
states and the retarget options into one strictly-descriptive DTO — no
verdict/score field by construction. Expose GET /api/medications/[id]/efficacy
and PUT /api/medications/[id]/efficacy/target, regenerate the OpenAPI contract.
Marc-André Bombeck